Ensembl ID ENSG00000143314 Gene ID 79590 Accession 14037
Gene Symbol MRPL24 Alias L24mt;uL24m;MRP-L18;MRP-L24 Full Name mitochondrial ribosomal protein L24
Position 1 : 156737303 - 156741590 Length 4288 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]

ENSG00000143314 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000143314 MRPL24 1.07 1.03e-45 BRCA
ENSG00000143314 MRPL24 1.02 6.03e-27 LUSC
ENSG00000143314 MRPL24 1.08 5.73e-26 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000143314 MRPL24 SARC 0.034 low
ENSG00000143314 MRPL24 CHOL 0.041 high
ENSG00000143314 MRPL24 PAAD 0.0034 high
ENSG00000143314 MRPL24 UCEC 0.028 high
ENSG00000143314 MRPL24 LGG 0.0014 low
ENSG00000143314 MRPL24 LUSC 0.025 low
ENSG00000143314 MRPL24 HNSC 0.035 high
ENSG00000143314 MRPL24 KIRP 0.015 low
ENSG00000143314 MRPL24 KICH 0.00062 high
ENSG00000143314 MRPL24 PCPG 0.01 high
ENSG00000143314 MRPL24 THYM 0.023 high
ENSG00000143314 MRPL24 COAD 0.027 high
ENSG00000143314 MRPL24 UCS 0.034 high
ENSG00000143314 MRPL24 OV 0.016 low
ENSG00000143314 MRPL24 DLBC 0.013 low
ENSG00000143314 MRPL24 PRAD 0.014 high
ENSG00000143314 MRPL24 BLCA 0.031 low
ENSG00000143314 MRPL24 LAML 0.019 high
ENSG00000143314 MRPL24 SKCM 0.0046 high
ENSG00000143314 MRPL24 LIHC 0.014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000143314 MRPL24 CHOL Amp 0.763398 0.432674 0.995527 0.611111
ENSG00000143314 MRPL24 LUSC Amp 2.115512 0.238832 0.530033 0.520958
ENSG00000143314 MRPL24 LUAD Amp 11.780441 0.299144 0.567358 0.720930
ENSG00000143314 MRPL24 LGG Amp 1.068291 0.049421 0.553095 0.079922
ENSG00000143314 MRPL24 CESC Amp 2.224565 0.186473 0.610429 0.542373
ENSG00000143314 MRPL24 SARC Amp 2.691448 0.360501 0.699754 0.357977
ENSG00000143314 MRPL24 SKCM Amp 2.008858 0.161853 0.679995 0.542234
ENSG00000143314 MRPL24 LIHC Amp 16.403934 0.375742 0.900426 0.748649
ENSG00000143314 MRPL24 PCPG Amp 0.826699 0.073017 0.648739 0.160494
ENSG00000143314 MRPL24 TGCT Amp 0.676527 0.115643 0.451044 0.453333
ENSG00000143314 MRPL24 DLBC Amp 1.852987 0.292853 0.670338 0.270833
ENSG00000143314 MRPL24 BLCA Amp 6.300963 0.317641 0.548195 0.443627
ENSG00000143314 MRPL24 BRCA Amp 16.377195 0.320748 0.782119 0.720370
ENSG00000143314 MRPL24 STAD Amp 1.042485 0.142050 0.438634 0.356009
ENSG00000143314 MRPL24 UCEC Amp 7.250454 0.213107 0.853615 0.448980
ENSG00000143314 MRPL24 OV Amp 5.034348 0.451473 0.680435 0.588946