Ensembl ID
ENSG00000143194
Gene ID
84944
Accession
25929
Gene Symbol
MAEL
Alias
CT128;SPATA35
Full Name
maelstrom spermatogenic transposon silencer
Position
1 : 166975582 - 167022214
Length
46633 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs ncRNA RBP type
Canonical_RBPs
Summary
Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in gamete generation; negative regulation of macromolecule metabolic process; and piRNA metabolic process. Predicted to act upstream of or within several processes, including homologous chromosome pairing at meiosis; intrinsic apoptotic signaling pathway in response to DNA damage; and negative regulation of macromolecule metabolic process. Predicted to be located in piP-body. Predicted to be active in P granule and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000143194 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000143194
MAEL
2.12
9.57e-23
BRCA
ENSG00000143194
MAEL
2.85
8.53e-13
LUSC
ENSG00000143194
MAEL
-1.4
6.59e-13
PRAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000143194
MAEL
cancer
19693694
ENSG00000143194
MAEL
tumor
23929794
ENSG00000143194
MAEL
cancer
24189637
ENSG00000143194
MAEL
cancer
24932571
ENSG00000143194
MAEL
cancer
27181205
ENSG00000143194
MAEL
colon cancer
27537253
ENSG00000143194
MAEL
breast cancer
27597120
ENSG00000143194
MAEL
cancer
28342986
ENSG00000143194
MAEL
gastric cancer
29371914
ENSG00000143194
MAEL
tumor
30082413
ENSG00000143194
MAEL
tumor
30488287
ENSG00000143194
MAEL
cancer
31386627
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000143194
MAEL
SARC
0.0099
low
show
ENSG00000143194
MAEL
UVM
0.025
high
show
ENSG00000143194
MAEL
ACC
0.0072
low
show
ENSG00000143194
MAEL
KIRP
0.035
high
show
ENSG00000143194
MAEL
LUAD
2e-04
low
show
ENSG00000143194
MAEL
PCPG
0.0091
low
show
ENSG00000143194
MAEL
THYM
0.012
high
show
ENSG00000143194
MAEL
COAD
0.04
low
show
ENSG00000143194
MAEL
OV
0.014
low
show
ENSG00000143194
MAEL
DLBC
0.023
high
show
ENSG00000143194
MAEL
KIRC
0.0026
low
show
ENSG00000143194
MAEL
LAML
0.027
high
show
ENSG00000143194
MAEL
SKCM
0.0034
low
show
ENSG00000143194
MAEL
CESC
0.049
low
show
ENSG00000143194
MAEL
LIHC
0.0031
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000143194
MAEL
LUSC
Amp
2.577609
0.251010
0.545879
0.516966
ENSG00000143194
MAEL
LUAD
Amp
2.815342
0.165806
0.516103
0.703488
ENSG00000143194
MAEL
CESC
Amp
1.021671
0.141371
0.599892
0.535593
ENSG00000143194
MAEL
SARC
Amp
5.167061
0.460746
0.804320
0.354086
ENSG00000143194
MAEL
SKCM
Amp
1.889389
0.158563
0.695308
0.534060
ENSG00000143194
MAEL
LIHC
Amp
10.078099
0.289657
0.883830
0.743243
ENSG00000143194
MAEL
DLBC
Amp
2.161985
0.327242
0.632842
0.312500
ENSG00000143194
MAEL
BLCA
Amp
19.269683
0.544293
0.724167
0.482843
ENSG00000143194
MAEL
BRCA
Amp
9.925599
0.264043
0.777229
0.738889
ENSG00000143194
MAEL
UCEC
Amp
2.341180
0.139662
0.825094
0.441558
ENSG00000143194
MAEL
OV
Amp
1.458060
0.356384
0.654851
0.556131
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.