Ensembl ID ENSG00000141759 Gene ID 10907 Accession 30551
Gene Symbol TXNL4A Alias BMKS;DIB1;DIM1;TXNL4;SNRNP15;U5-15kD Full Name thioredoxin like 4A
Position 18 : 79970813 - 80033949 Length 63137 bases Strand Minus strand
Status Confidence Main interacting RNAssnRNARBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1). Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]

ENSG00000141759 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000141759 TXNL4A 0.70 8.73e-30 BRCA
ENSG00000141759 TXNL4A 1.03 3.16e-25 KICH
ENSG00000141759 TXNL4A 1.23 3.39e-31 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000141759 TXNL4A MESO 0.0035 high
ENSG00000141759 TXNL4A SARC 0.036 high
ENSG00000141759 TXNL4A PAAD 0.0031 low
ENSG00000141759 TXNL4A THCA 0.049 low
ENSG00000141759 TXNL4A LGG 0.0036 low
ENSG00000141759 TXNL4A KIRP 0.025 low
ENSG00000141759 TXNL4A COAD 0.007 low
ENSG00000141759 TXNL4A ESCA 0.011 high
ENSG00000141759 TXNL4A OV 0.0031 low
ENSG00000141759 TXNL4A DLBC 0.0064 low
ENSG00000141759 TXNL4A KIRC 0.00024 high
ENSG00000141759 TXNL4A PRAD 0.03 high
ENSG00000141759 TXNL4A LAML 0.033 high
ENSG00000141759 TXNL4A GBM 0.0042 high
ENSG00000141759 TXNL4A SKCM 0.001 high
ENSG00000141759 TXNL4A CESC 0.0029 low
ENSG00000141759 TXNL4A LIHC 0.00022 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency