Ensembl ID ENSG00000141279 Gene ID 9520 Accession 7900
Gene Symbol NPEPPS Alias PSA;AAP-S;MP100 Full Name aminopeptidase puromycin sensitive
Position 17 : 47522942 - 47624665 Length 101724 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008]

ENSG00000141279 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000141279 NPEPPS -0.7 4.55e-13 HNSC
ENSG00000141279 NPEPPS 0.41 3.30e-11 LUSC
ENSG00000141279 NPEPPS 0.62 1.65e-20 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000141279 NPEPPS tumor 16985214
ENSG00000141279 NPEPPS pancreatic cancer 23071732
ENSG00000141279 NPEPPS tumor 23154538
ENSG00000141279 NPEPPS cancer 24385243
ENSG00000141279 NPEPPS tumor 26078706
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000141279 NPEPPS MESO 0.044 low
ENSG00000141279 NPEPPS STAD 0.046 low
ENSG00000141279 NPEPPS PAAD 0.0046 high
ENSG00000141279 NPEPPS UCEC 0.011 high
ENSG00000141279 NPEPPS THCA 0.011 low
ENSG00000141279 NPEPPS LUSC 0.039 high
ENSG00000141279 NPEPPS READ 0.004 low
ENSG00000141279 NPEPPS COAD 0.00033 low
ENSG00000141279 NPEPPS KIRC 0.024 low
ENSG00000141279 NPEPPS PRAD 0.019 high
ENSG00000141279 NPEPPS LAML 0.0057 low
ENSG00000141279 NPEPPS CESC 0.023 high
ENSG00000141279 NPEPPS LIHC 0.00013 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000141279 NPEPPS BRCA Del 1.003051 0.066362 0.406140 0.277778
ENSG00000141279 NPEPPS UCEC Del 1.794502 0.061263 0.543299 0.183673