Ensembl ID ENSG00000141279 Gene ID 9520 Accession 7900
Gene Symbol NPEPPS Alias PSA;AAP-S;MP100 Full Name aminopeptidase puromycin sensitive
Position 17 : 47522942 - 47624665 Length 101724 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008]

ENSG00000141279 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000141279 -0.7 4.55e-13 HNSC
ENSG00000141279 0.41 3.30e-11 LUSC
ENSG00000141279 0.62 1.65e-20 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000141279 tumor 16985214
ENSG00000141279 pancreatic cancer 23071732
ENSG00000141279 tumor 23154538
ENSG00000141279 cancer 24385243
ENSG00000141279 tumor 26078706
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000141279 MESO 0.044 low
ENSG00000141279 STAD 0.046 low
ENSG00000141279 PAAD 0.0046 high
ENSG00000141279 UCEC 0.011 high
ENSG00000141279 THCA 0.011 low
ENSG00000141279 LUSC 0.039 high
ENSG00000141279 READ 0.004 low
ENSG00000141279 COAD 0.00033 low
ENSG00000141279 KIRC 0.024 low
ENSG00000141279 PRAD 0.019 high
ENSG00000141279 LAML 0.0057 low
ENSG00000141279 CESC 0.023 high
ENSG00000141279 LIHC 0.00013 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000141279 BRCA Del 1.003051 0.066362 0.406140 0.277778
ENSG00000141279 UCEC Del 1.794502 0.061263 0.543299 0.183673