Ensembl ID ENSG00000141101 Gene ID 28987 Accession 29540
Gene Symbol NOB1 Alias ART-4;NOB1P;MST158;MSTP158;PSMD8BP1 Full Name NIN1 (RPN12) binding protein 1 homolog
Position 16 : 69741871 - 69754926 Length 13056 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010]

ENSG00000141101 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000141101 NOB1 0.37 4.75e-13 KIRC
ENSG00000141101 NOB1 -0.4 3.11e-14 BRCA
ENSG00000141101 NOB1 1.17 3.11e-39 COAD
ENSG00000141101 NOB1 1.23 1.14e-16 READ
ENSG00000141101 NOB1 0.99 6.34e-37 LUSC
ENSG00000141101 NOB1 0.69 1.04e-18 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000141101 NOB1 ovarian cancer 21287298
ENSG00000141101 NOB1 colorectal cancer 22445998
ENSG00000141101 NOB1 breast cancer 22901129
ENSG00000141101 NOB1 colon cancer 23172535
ENSG00000141101 NOB1 tumour 23685895
ENSG00000141101 NOB1 Tumor 23869222
ENSG00000141101 NOB1 tumor 24133592
ENSG00000141101 NOB1 prostate cancer 24228091
ENSG00000141101 NOB1 non-small-cell lung cancer 24272676
ENSG00000141101 NOB1 tumor 24452698
ENSG00000141101 NOB1 colon cancer 24824907
ENSG00000141101 NOB1 renal cancer 25010867
ENSG00000141101 NOB1 prostate cancer 25169742
ENSG00000141101 NOB1 tumor 25231838
ENSG00000141101 NOB1 tumor 25420906
ENSG00000141101 NOB1 non-small cell lung cancer 25450647
ENSG00000141101 NOB1 prostate cancer 25503472
ENSG00000141101 NOB1 cancer 25592304
ENSG00000141101 NOB1 colorectal cancer 25624720
ENSG00000141101 NOB1 tumor 25760058
ENSG00000141101 NOB1 non-small cell lung cancer 25971309
ENSG00000141101 NOB1 non-small cell lung cancer 26178254
ENSG00000141101 NOB1 cancer 26370469
ENSG00000141101 NOB1 epithelial ovarian cancer 26617713
ENSG00000141101 NOB1 prostate cancer 26743688
ENSG00000141101 NOB1 laryngeal cancer 27035645
ENSG00000141101 NOB1 gastric cancer 27097067
ENSG00000141101 NOB1 Non-small Cell Lung Cancer 27346559
ENSG00000141101 NOB1 cervical cancer 27505862
ENSG00000141101 NOB1 Gastric Cancer 27733214
ENSG00000141101 NOB1 epithelial ovarian cancer 28337275
ENSG00000141101 NOB1 non-small cell lung cancer 28849232
ENSG00000141101 NOB1 tumor 29115574
ENSG00000141101 NOB1 ovarian cancer 29254193
ENSG00000141101 NOB1 colorectal cancer 29391877
ENSG00000141101 NOB1 tumor 29467874
ENSG00000141101 NOB1 small-cell lung cancer 29749434
ENSG00000141101 NOB1 Gastric Cancer 30274015
ENSG00000141101 NOB1 tumor 30555741
ENSG00000141101 NOB1 papillary thyroid cancer 30628685
ENSG00000141101 NOB1 Cancer 30854959
ENSG00000141101 NOB1 cancer 31068824
ENSG00000141101 NOB1 tumor 31568401
ENSG00000141101 NOB1 Colorectal Cancer 31906747
ENSG00000141101 NOB1 cervical cancer 31970934
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000141101 NOB1 MESO 0.015 low
ENSG00000141101 NOB1 STAD 0.018 low
ENSG00000141101 NOB1 UVM 0.024 low
ENSG00000141101 NOB1 PAAD 0.0041 high
ENSG00000141101 NOB1 UCEC 0.013 high
ENSG00000141101 NOB1 THCA 0.0049 low
ENSG00000141101 NOB1 ACC 0.00092 high
ENSG00000141101 NOB1 LGG 0.0034 low
ENSG00000141101 NOB1 READ 0.013 low
ENSG00000141101 NOB1 KIRP 0.0027 high
ENSG00000141101 NOB1 KICH 0.0043 low
ENSG00000141101 NOB1 LUAD 0.04 high
ENSG00000141101 NOB1 PCPG 0.0049 low
ENSG00000141101 NOB1 KIRC 0.033 low
ENSG00000141101 NOB1 TGCT 0.01 high
ENSG00000141101 NOB1 GBM 0.027 low
ENSG00000141101 NOB1 CESC 0.034 high
ENSG00000141101 NOB1 LIHC 0.0035 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000141101 NOB1 LAML Del 1.466386 0.041379 0.608754 0.036649
ENSG00000141101 NOB1 ACC Amp 0.698720 0.245863 1.076298 0.577778
ENSG00000141101 NOB1 TGCT Amp 0.748581 0.119204 0.578998 0.140000
ENSG00000141101 NOB1 BLCA Amp 0.840071 0.169467 0.485554 0.259804
ENSG00000141101 NOB1 PRAD Del 6.188774 0.123889 0.519837 0.308943
ENSG00000141101 NOB1 UCEC Del 4.129835 0.082153 0.636102 0.280148
ENSG00000141101 NOB1 OV Del 12.031520 0.318624 0.655055 0.772021