Ensembl ID ENSG00000139718 Gene ID 23067 Accession 29187
Gene Symbol SETD1B Alias KMT2G;Set1B;IDDSELD Full Name SET domain containing 1B, histone lysine methyltransferase
Position 12 : 121804009 - 121832656 Length 28648 bases Strand Plus strand
Status Confidence Main interacting RNAsncRNARBP type Canonical_RBPs
Summary SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Mar 2008]

ENSG00000139718 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000139718 SETD1B 0.88 1.71e-15 KICH
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000139718 SETD1B colorectal cancers 24925220
ENSG00000139718 SETD1B endometrial cancer 27997699
ENSG00000139718 SETD1B tumor 28381543
ENSG00000139718 SETD1B cancers 29138278
ENSG00000139718 SETD1B metastatic tumor 29944950
ENSG00000139718 SETD1B tumor 30628696
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000139718 SETD1B lung adenocarcinoma stop_gained 1.289% (15/1164) 2 entries
ENSG00000139718 SETD1B Pancreatic Acinar Cell Carcinoma missense_variant 10.0% (2/20) 2 entries
ENSG00000139718 SETD1B colon adenocarcinoma missense_variant 3.366% (24/713) 3 entries
ENSG00000139718 SETD1B Merkel cell skin cancer missense_variant 10.0% (3/30) 2 entries
ENSG00000139718 SETD1B colorectal adenocarcinoma missense_variant 3.078% (35/1137) 2 entries
ENSG00000139718 SETD1B oral squamous cell carcinoma missense_variant 2.415% (5/207) 4 entries
ENSG00000139718 SETD1B female breast carcinoma stop_gained 1.124% (3/267) 1 entry
ENSG00000139718 SETD1B gastric intestinal type adenocarcinoma missense_variant 5.882% (5/85) 1 entry
ENSG00000139718 SETD1B clear cell renal carcinoma missense_variant 0.2278% (3/1317) 1 entry
ENSG00000139718 SETD1B gastric intestinal type adenocarcinoma frameshift_variant 5.882% (5/85) 1 entry
ENSG00000139718 SETD1B hepatocellular carcinoma missense_variant 0.7778% (7/900) 1 entry
ENSG00000139718 SETD1B chromophobe renal cell carcinoma missense_variant 1.754% (2/114) 1 entry
ENSG00000139718 SETD1B prostate adenocarcinoma frameshift_variant 0.6878% (10/1454) 2 entries
ENSG00000139718 SETD1B lung adenocarcinoma missense_variant 1.289% (15/1164) 5 entries
ENSG00000139718 SETD1B prostate carcinoma frameshift_variant 2.347% (10/426) 1 entry
ENSG00000139718 SETD1B head and neck squamous cell carcinoma missense_variant 0.4792% (3/626) 1 entry
ENSG00000139718 SETD1B squamous cell lung carcinoma missense_variant 0.3937% (3/762) 1 entry
ENSG00000139718 SETD1B acute lymphoblastic leukemia missense_variant 0.6231% (2/321) 1 entry
ENSG00000139718 SETD1B esophageal squamous cell carcinoma missense_variant 1.481% (10/675) 3 entries
ENSG00000139718 SETD1B brain glioblastoma sequence_alteration 0.6479% (6/926) 1 entry
ENSG00000139718 SETD1B colorectal adenocarcinoma frameshift_variant 3.078% (35/1137) 1 entry
ENSG00000139718 SETD1B bile duct adenocarcinoma missense_variant 1.058% (2/189) 1 entry
ENSG00000139718 SETD1B prostate carcinoma sequence_alteration 2.347% (10/426) 1 entry
ENSG00000139718 SETD1B colon adenocarcinoma frameshift_variant 3.366% (24/713) 2 entries
ENSG00000139718 SETD1B diffuse large B-cell lymphoma missense_variant 1.645% (5/304) 3 entries
ENSG00000139718 SETD1B prostate carcinoma missense_variant 2.347% (10/426) 1 entry
ENSG00000139718 SETD1B pancreatic ductal adenocarcinoma missense_variant 1.509% (19/1259) 1 entry
ENSG00000139718 SETD1B Endometrial Endometrioid Adenocarcinoma frameshift_variant 3.085% (17/551) 1 entry
ENSG00000139718 SETD1B acute myeloid leukemia missense_variant 0.9891% (10/1011) 1 entry
ENSG00000139718 SETD1B skin melanoma missense_variant 0.5171% (5/967) 3 entries
ENSG00000139718 SETD1B prostate adenocarcinoma missense_variant 0.6878% (10/1454) 2 entries
ENSG00000139718 SETD1B neoplasm missense_variant 3.571% (1/28) 1 entry
ENSG00000139718 SETD1B nasopharyngeal squamous cell carcinoma conservative_inframe_deletion 0.5988% (1/167) 1 entry
ENSG00000139718 SETD1B colorectal adenocarcinoma stop_gained 3.078% (35/1137) 1 entry
ENSG00000139718 SETD1B female breast carcinoma missense_variant 1.124% (3/267) 1 entry
ENSG00000139718 SETD1B T-cell acute lymphoblastic leukemia frameshift_variant 0.2632% (1/380) 1 entry
ENSG00000139718 SETD1B small cell lung carcinoma sequence_alteration 0.9434% (3/318) 1 entry
ENSG00000139718 SETD1B gastric intestinal type adenocarcinoma stop_gained 5.882% (5/85) 1 entry
ENSG00000139718 SETD1B bronchoalveolar adenocarcinoma missense_variant 4.545% (1/22) 1 entry
ENSG00000139718 SETD1B clear cell renal carcinoma frameshift_variant 0.2278% (3/1317) 1 entry
ENSG00000139718 SETD1B small cell lung carcinoma frameshift_variant 0.9434% (3/318) 1 entry
ENSG00000139718 SETD1B primary peritoneal carcinoma (disease) frameshift_variant 100.0% (1/1) 1 entry
ENSG00000139718 SETD1B colon adenocarcinoma sequence_alteration 3.366% (24/713) 1 entry
ENSG00000139718 SETD1B primary peritoneal carcinoma (disease) missense_variant 100.0% (1/1) 1 entry
ENSG00000139718 SETD1B diffuse large B-cell lymphoma stop_gained 1.645% (5/304) 1 entry
ENSG00000139718 SETD1B Pleural Epithelioid Mesothelioma sequence_alteration 1.064% (1/94) 1 entry
ENSG00000139718 SETD1B neoplasm of mature B-cells missense_variant 2.941% (1/34) 1 entry
ENSG00000139718 SETD1B colonic neoplasm missense_variant 6.667% (1/15) 1 entry
ENSG00000139718 SETD1B Parathyroid Gland Carcinoma conservative_inframe_deletion 7.692% (2/26) 1 entry
ENSG00000139718 SETD1B B-cell acute lymphoblastic leukemia missense_variant 1.852% (1/54) 1 entry
ENSG00000139718 SETD1B non-small cell lung carcinoma stop_gained 1.887% (1/53) 1 entry
ENSG00000139718 SETD1B small cell lung carcinoma missense_variant 0.9434% (3/318) 1 entry
ENSG00000139718 SETD1B acute myeloid leukemia frameshift_variant 0.9891% (10/1011) 1 entry
ENSG00000139718 SETD1B colon adenocarcinoma stop_gained 3.366% (24/713) 1 entry
ENSG00000139718 SETD1B lung carcinoid tumor missense_variant 9.091% (1/11) 1 entry
ENSG00000139718 SETD1B Parathyroid Gland Carcinoma missense_variant 7.692% (2/26) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000139718 SETD1B PAAD 9e-04 low
ENSG00000139718 SETD1B LGG 0.042 high
ENSG00000139718 SETD1B HNSC 0.0081 low
ENSG00000139718 SETD1B KICH 0.042 low
ENSG00000139718 SETD1B LUAD 0.016 high
ENSG00000139718 SETD1B PCPG 0.023 low
ENSG00000139718 SETD1B THYM 0.0028 low
ENSG00000139718 SETD1B COAD 0.019 high
ENSG00000139718 SETD1B UCS 0.015 low
ENSG00000139718 SETD1B ESCA 0.021 low
ENSG00000139718 SETD1B OV 0.045 high
ENSG00000139718 SETD1B GBM 0.036 high
ENSG00000139718 SETD1B SKCM 0.0063 high
ENSG00000139718 SETD1B LIHC 0.016 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000139718 SETD1B LUSC Del 0.765700 0.066558 0.296051 0.173653
ENSG00000139718 SETD1B LUAD Del 0.923624 0.054552 0.282554 0.240310
ENSG00000139718 SETD1B UCS Del 1.026234 0.230063 0.562014 0.339286
ENSG00000139718 SETD1B PAAD Del 1.194446 0.055898 0.346565 0.222826
ENSG00000139718 SETD1B LIHC Del 1.556502 0.079589 0.422642 0.140541
ENSG00000139718 SETD1B BRCA Del 4.480194 0.089920 0.377026 0.201852
ENSG00000139718 SETD1B UCEC Del 3.676037 0.078336 0.416181 0.129870
ENSG00000139718 SETD1B OV Del 4.714378 0.243082 0.574963 0.333333