Ensembl ID ENSG00000139546 Gene ID 6895 Accession 11569
Gene Symbol TARBP2 Alias LOQS;TRBP;TRBP1;TRBP2 Full Name TARBP2 subunit of RISC loading complex
Position 12 : 53500921 - 53506431 Length 5511 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]

ENSG00000139546 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000139546 TARBP2 1.08 3.85e-16 BLCA
ENSG00000139546 TARBP2 0.71 3.04e-34 BRCA
ENSG00000139546 TARBP2 0.92 6.90e-17 COAD
ENSG00000139546 TARBP2 0.90 1.29e-30 LUSC
ENSG00000139546 TARBP2 0.53 1.22e-15 PRAD
ENSG00000139546 TARBP2 0.73 2.58e-12 KIRP
ENSG00000139546 TARBP2 0.99 6.15e-21 UCEC
ENSG00000139546 TARBP2 0.70 6.24e-16 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000139546 TARBP2 tumor 15123692
ENSG00000139546 TARBP2 cancer 19219043
ENSG00000139546 TARBP2 colorectal cancer 20101446
ENSG00000139546 TARBP2 cancer 20198652
ENSG00000139546 TARBP2 tumor 20485546
ENSG00000139546 TARBP2 cancer 21368194
ENSG00000139546 TARBP2 skin cancer 22025453
ENSG00000139546 TARBP2 cancer 22698405
ENSG00000139546 TARBP2 cancers 22719182
ENSG00000139546 TARBP2 tumors 23543617
ENSG00000139546 TARBP2 adrenocortical tumors 23671264
ENSG00000139546 TARBP2 DLBCLs 24121164
ENSG00000139546 TARBP2 breast cancer 24563327
ENSG00000139546 TARBP2 cancer 25043050
ENSG00000139546 TARBP2 tumor 26087193
ENSG00000139546 TARBP2 cancer 26308063
ENSG00000139546 TARBP2 cancers 26486325
ENSG00000139546 TARBP2 tumour 26582366
ENSG00000139546 TARBP2 tumors 26688807
ENSG00000139546 TARBP2 Tumors 27453764
ENSG00000139546 TARBP2 small cell lung cancer 27599909
ENSG00000139546 TARBP2 Breast Cancer 27980417
ENSG00000139546 TARBP2 cancer 28096385
ENSG00000139546 TARBP2 tumor 28115942
ENSG00000139546 TARBP2 tumor 29020972
ENSG00000139546 TARBP2 cancer 29467169
ENSG00000139546 TARBP2 cancer 30397354
ENSG00000139546 TARBP2 tumors 30657254
ENSG00000139546 TARBP2 Breast Cancer 30759864
ENSG00000139546 TARBP2 thyroid tumors 30956758
ENSG00000139546 TARBP2 tumor 31300274
ENSG00000139546 TARBP2 tumors 31510013
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000139546 TARBP2 MESO 0.014 high
ENSG00000139546 TARBP2 STAD 0.029 low
ENSG00000139546 TARBP2 CHOL 0.025 high
ENSG00000139546 TARBP2 UVM 0.007 high
ENSG00000139546 TARBP2 PAAD 0.018 low
ENSG00000139546 TARBP2 UCEC 0.022 high
ENSG00000139546 TARBP2 ACC 0.002 high
ENSG00000139546 TARBP2 LGG 0.00031 high
ENSG00000139546 TARBP2 HNSC 0.016 high
ENSG00000139546 TARBP2 READ 0.0053 low
ENSG00000139546 TARBP2 KICH 0.00016 high
ENSG00000139546 TARBP2 PCPG 0.0031 low
ENSG00000139546 TARBP2 COAD 0.05 high
ENSG00000139546 TARBP2 UCS 0.018 low
ENSG00000139546 TARBP2 ESCA 0.0073 low
ENSG00000139546 TARBP2 DLBC 0.016 low
ENSG00000139546 TARBP2 PRAD 0.04 low
ENSG00000139546 TARBP2 SKCM 0.0018 high
ENSG00000139546 TARBP2 LIHC 0.00058 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency