Ensembl ID
ENSG00000139546
Gene ID
6895
Accession
11569
Gene Symbol
TARBP2
Alias
LOQS;TRBP;TRBP1;TRBP2
Full Name
TARBP2 subunit of RISC loading complex
Position
12 : 53500921 - 53506431
Length
5511 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]
ENSG00000139546 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000139546
TARBP2
1.08
3.85e-16
BLCA
ENSG00000139546
TARBP2
0.71
3.04e-34
BRCA
ENSG00000139546
TARBP2
0.92
6.90e-17
COAD
ENSG00000139546
TARBP2
0.90
1.29e-30
LUSC
ENSG00000139546
TARBP2
0.53
1.22e-15
PRAD
ENSG00000139546
TARBP2
0.73
2.58e-12
KIRP
ENSG00000139546
TARBP2
0.99
6.15e-21
UCEC
ENSG00000139546
TARBP2
0.70
6.24e-16
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000139546
TARBP2
tumor
15123692
ENSG00000139546
TARBP2
cancer
19219043
ENSG00000139546
TARBP2
colorectal cancer
20101446
ENSG00000139546
TARBP2
cancer
20198652
ENSG00000139546
TARBP2
tumor
20485546
ENSG00000139546
TARBP2
cancer
21368194
ENSG00000139546
TARBP2
skin cancer
22025453
ENSG00000139546
TARBP2
cancer
22698405
ENSG00000139546
TARBP2
cancers
22719182
ENSG00000139546
TARBP2
tumors
23543617
ENSG00000139546
TARBP2
adrenocortical tumors
23671264
ENSG00000139546
TARBP2
DLBCLs
24121164
ENSG00000139546
TARBP2
breast cancer
24563327
ENSG00000139546
TARBP2
cancer
25043050
ENSG00000139546
TARBP2
tumor
26087193
ENSG00000139546
TARBP2
cancer
26308063
ENSG00000139546
TARBP2
cancers
26486325
ENSG00000139546
TARBP2
tumour
26582366
ENSG00000139546
TARBP2
tumors
26688807
ENSG00000139546
TARBP2
Tumors
27453764
ENSG00000139546
TARBP2
small cell lung cancer
27599909
ENSG00000139546
TARBP2
Breast Cancer
27980417
ENSG00000139546
TARBP2
cancer
28096385
ENSG00000139546
TARBP2
tumor
28115942
ENSG00000139546
TARBP2
tumor
29020972
ENSG00000139546
TARBP2
cancer
29467169
ENSG00000139546
TARBP2
cancer
30397354
ENSG00000139546
TARBP2
tumors
30657254
ENSG00000139546
TARBP2
Breast Cancer
30759864
ENSG00000139546
TARBP2
thyroid tumors
30956758
ENSG00000139546
TARBP2
tumor
31300274
ENSG00000139546
TARBP2
tumors
31510013
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000139546
TARBP2
MESO
0.014
high
show
ENSG00000139546
TARBP2
STAD
0.029
low
show
ENSG00000139546
TARBP2
CHOL
0.025
high
show
ENSG00000139546
TARBP2
UVM
0.007
high
show
ENSG00000139546
TARBP2
PAAD
0.018
low
show
ENSG00000139546
TARBP2
UCEC
0.022
high
show
ENSG00000139546
TARBP2
ACC
0.002
high
show
ENSG00000139546
TARBP2
LGG
0.00031
high
show
ENSG00000139546
TARBP2
HNSC
0.016
high
show
ENSG00000139546
TARBP2
READ
0.0053
low
show
ENSG00000139546
TARBP2
KICH
0.00016
high
show
ENSG00000139546
TARBP2
PCPG
0.0031
low
show
ENSG00000139546
TARBP2
COAD
0.05
high
show
ENSG00000139546
TARBP2
UCS
0.018
low
show
ENSG00000139546
TARBP2
ESCA
0.0073
low
show
ENSG00000139546
TARBP2
DLBC
0.016
low
show
ENSG00000139546
TARBP2
PRAD
0.04
low
show
ENSG00000139546
TARBP2
SKCM
0.0018
high
show
ENSG00000139546
TARBP2
LIHC
0.00058
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
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