Ensembl ID ENSG00000138768 Gene ID 8615 Accession 30904
Gene Symbol USO1 Alias TAP;VDP;P115 Full Name USO1 vesicle transport factor
Position 4 : 75724577 - 75814286 Length 89710 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

ENSG00000138768 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000138768 -0.8 1.53e-22 HNSC
ENSG00000138768 0.86 1.75e-12 KICH
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000138768 tumor 25437370
ENSG00000138768 colon cancer 26184508
ENSG00000138768 tumor 26898451
ENSG00000138768 liver cancer 28529566
ENSG00000138768 breast cancer 29249802
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000138768 MESO 0.0081 low
ENSG00000138768 SARC 0.018 high
ENSG00000138768 PAAD 0.028 high
ENSG00000138768 UCEC 0.036 low
ENSG00000138768 LUSC 0.024 high
ENSG00000138768 READ 0.038 low
ENSG00000138768 KIRP 0.047 high
ENSG00000138768 BRCA 0.011 high
ENSG00000138768 COAD 0.0096 low
ENSG00000138768 UCS 0.014 high
ENSG00000138768 OV 0.04 high
ENSG00000138768 TGCT 0.045 high
ENSG00000138768 BLCA 0.023 low
ENSG00000138768 LAML 0.0031 low
ENSG00000138768 SKCM 0.00033 low
ENSG00000138768 CESC 0.038 high
ENSG00000138768 LIHC 0.007 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000138768 LUSC Amp 1.671976 0.225867 0.669967 0.155689
ENSG00000138768 LIHC Del 2.874196 0.097146 0.553998 0.418919