Ensembl ID ENSG00000138668 Gene ID 3184 Accession 5036
Gene Symbol HNRNPD Alias P37;AUF1;AUF1A;HNRPD;hnRNPD0 Full Name heterogeneous nuclear ribonucleoprotein D
Position 4 : 82352498 - 82374503 Length 22006 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]

ENSG00000138668 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000138668 HNRNPD 0.28 1.72e-12 KIRC
ENSG00000138668 HNRNPD 0.54 3.72e-16 COAD
ENSG00000138668 HNRNPD 0.55 6.09e-16 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000138668 HNRNPD tumors 11888925
ENSG00000138668 HNRNPD tumor 14585195
ENSG00000138668 HNRNPD breast cancer 16289864
ENSG00000138668 HNRNPD cancer 18829526
ENSG00000138668 HNRNPD cancers 19491267
ENSG00000138668 HNRNPD tumor 19574297
ENSG00000138668 HNRNPD cancer 20157551
ENSG00000138668 HNRNPD cancer 20495997
ENSG00000138668 HNRNPD cancer 21622178
ENSG00000138668 HNRNPD cancer 21736933
ENSG00000138668 HNRNPD tumor 21799732
ENSG00000138668 HNRNPD breast cancer 22431556
ENSG00000138668 HNRNPD breast cancer 22751126
ENSG00000138668 HNRNPD cancers 23066106
ENSG00000138668 HNRNPD tumors 23696003
ENSG00000138668 HNRNPD cancer 23894605
ENSG00000138668 HNRNPD tumors 24213928
ENSG00000138668 HNRNPD lung cancer 24564251
ENSG00000138668 HNRNPD cancer 25159612
ENSG00000138668 HNRNPD breast cancer 25231991
ENSG00000138668 HNRNPD tumor 25261470
ENSG00000138668 HNRNPD cancer 25366541
ENSG00000138668 HNRNPD cancer 27248826
ENSG00000138668 HNRNPD cancer 27251431
ENSG00000138668 HNRNPD cancers 27578251
ENSG00000138668 HNRNPD thyroid cancer 27683118
ENSG00000138668 HNRNPD colon cancer 27784781
ENSG00000138668 HNRNPD tumor 27826622
ENSG00000138668 HNRNPD tumor 29599909
ENSG00000138668 HNRNPD tumor 30524947
ENSG00000138668 HNRNPD ovarian cancer 30678426
ENSG00000138668 HNRNPD Cancer 30681073
ENSG00000138668 HNRNPD cancer 30799487
ENSG00000138668 HNRNPD tumor 31016112
ENSG00000138668 HNRNPD tumor 31023373
ENSG00000138668 HNRNPD bladder cancer 31071529
ENSG00000138668 HNRNPD gastric cancer 31657090
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000138668 HNRNPD SARC 0.0027 high
ENSG00000138668 HNRNPD STAD 0.05 low
ENSG00000138668 HNRNPD UVM 0.039 low
ENSG00000138668 HNRNPD PAAD 0.012 high
ENSG00000138668 HNRNPD READ 0.025 low
ENSG00000138668 HNRNPD KIRP 0.0071 high
ENSG00000138668 HNRNPD KICH 0.023 high
ENSG00000138668 HNRNPD LUAD 0.011 high
ENSG00000138668 HNRNPD THYM 0.0014 low
ENSG00000138668 HNRNPD BRCA 0.0018 low
ENSG00000138668 HNRNPD ESCA 0.0082 high
ENSG00000138668 HNRNPD OV 0.049 low
ENSG00000138668 HNRNPD PRAD 0.0038 high
ENSG00000138668 HNRNPD BLCA 0.012 low
ENSG00000138668 HNRNPD CESC 0.014 low
ENSG00000138668 HNRNPD LIHC 0.0035 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000138668 HNRNPD LIHC Del 4.517209 0.116165 0.557323 0.451351
ENSG00000138668 HNRNPD BLCA Del 1.304914 0.087567 0.342657 0.355392
ENSG00000138668 HNRNPD STAD Del 1.381522 0.070458 0.331018 0.412698
ENSG00000138668 HNRNPD OV Del 1.559031 0.194092 0.607944 0.613126