Ensembl ID ENSG00000138279 Gene ID 310 Accession 545
Gene Symbol ANXA7 Alias SNX;ANX7;SYNEXIN Full Name annexin A7
Position 10 : 73375101 - 73414067 Length 38967 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008]

ENSG00000138279 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000138279 -0.5 4.86e-28 KIRC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000138279 tumor 10744047
ENSG00000138279 tumor 11287641
ENSG00000138279 breast cancer 11673658
ENSG00000138279 prostate cancer 14608035
ENSG00000138279 tumor 14609169
ENSG00000138279 breast cancer 15073110
ENSG00000138279 tumor 15183540
ENSG00000138279 tumour 15585510
ENSG00000138279 familial prostate cancer 16267836
ENSG00000138279 Tumor 17018618
ENSG00000138279 tumor 17708571
ENSG00000138279 tumours 18071363
ENSG00000138279 tumor 18172276
ENSG00000138279 gastric cancer 18449914
ENSG00000138279 tumors 18854424
ENSG00000138279 tumors 18948577
ENSG00000138279 tumor 19427857
ENSG00000138279 tumor 19562801
ENSG00000138279 tumor 19602687
ENSG00000138279 prostate cancer 19610065
ENSG00000138279 tumors 19855434
ENSG00000138279 prostate cancer 20190808
ENSG00000138279 cancer 20225761
ENSG00000138279 tumor 21208906
ENSG00000138279 pediatric cancer 21796766
ENSG00000138279 breast cancer 21821931
ENSG00000138279 tumor 21908572
ENSG00000138279 tumors 22447251
ENSG00000138279 pancreatic cancer 22532868
ENSG00000138279 tumors 23540285
ENSG00000138279 tumour 23582794
ENSG00000138279 cancers 23639634
ENSG00000138279 cancer 23777986
ENSG00000138279 tumor 23809371
ENSG00000138279 tumor 24052074
ENSG00000138279 tumors 24188284
ENSG00000138279 cancers 24191862
ENSG00000138279 breast cancer 24280702
ENSG00000138279 tumors 24373698
ENSG00000138279 tumor 24392146
ENSG00000138279 tumor 24529848
ENSG00000138279 prostate cancer 24864229
ENSG00000138279 tumor 24865424
ENSG00000138279 cancer 24879994
ENSG00000138279 breast cancer 24963320
ENSG00000138279 tumors 25070395
ENSG00000138279 tumours 25262379
ENSG00000138279 esophageal cancer 25333998
ENSG00000138279 cancer 25334086
ENSG00000138279 prostate cancer 25339368
ENSG00000138279 gastric cancer 25400735
ENSG00000138279 tumor 25563492
ENSG00000138279 cancer 25579569
ENSG00000138279 tumor 25661391
ENSG00000138279 cancer 25848269
ENSG00000138279 cancer 25882846
ENSG00000138279 tumor 25936860
ENSG00000138279 tumor 26067607
ENSG00000138279 cancer 26918348
ENSG00000138279 gastric cancer 27188606
ENSG00000138279 cancer 27231263
ENSG00000138279 esophageal cancer 27420968
ENSG00000138279 liver cancer 27551759
ENSG00000138279 Tumor 27807828
ENSG00000138279 gastric cancer 28176245
ENSG00000138279 acute myeloid leukemia (AML) 28713903
ENSG00000138279 tumor 28915599
ENSG00000138279 prostate cancer 29247827
ENSG00000138279 lung cancer 29421063
ENSG00000138279 prostate cancer 29462943
ENSG00000138279 tumor 29783989
ENSG00000138279 breast cancer 29893423
ENSG00000138279 gastric cancer 29928357
ENSG00000138279 Prostate Cancer 29970503
ENSG00000138279 cancer 30194165
ENSG00000138279 prostate cancer 30321230
ENSG00000138279 cancer 30347600
ENSG00000138279 tumor 30369774
ENSG00000138279 AML 30694461
ENSG00000138279 Cervical Cancer 31019655
ENSG00000138279 invasive breast cancer 31040365
ENSG00000138279 tumors 31113013
ENSG00000138279 breast cancer 31182056
ENSG00000138279 gastric cancer 31217851
ENSG00000138279 ovarian cancer 31474227
ENSG00000138279 tumor 31581454
ENSG00000138279 cancer 31700053
ENSG00000138279 tumor 31819169
ENSG00000138279 tumors 31903741
ENSG00000138279 tumor 31958076
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000138279 MESO 0.02 low
ENSG00000138279 SARC 0.00035 low
ENSG00000138279 UVM 0.00026 high
ENSG00000138279 THCA 0.042 low
ENSG00000138279 ACC 0.015 high
ENSG00000138279 HNSC 0.04 low
ENSG00000138279 READ 0.017 high
ENSG00000138279 KIRP 0.0016 low
ENSG00000138279 UCS 0.004 high
ENSG00000138279 ESCA 0.043 high
ENSG00000138279 BLCA 0.031 high
ENSG00000138279 LAML 0.0055 high
ENSG00000138279 CESC 0.045 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000138279 THCA Del 1.956122 0.014971 0.506030 0.022044
ENSG00000138279 STAD Amp 2.785193 0.189046 0.600480 0.197279
ENSG00000138279 UCEC Amp 0.633781 0.100941 0.673179 0.228200