Ensembl ID ENSG00000138231 Gene ID 51163 Accession 15594
Gene Symbol DBR1 Alias NA Full Name debranching RNA lariats 1
Position 3 : 138160988 - 138174949 Length 13962 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2'-5' prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication. [provided by RefSeq, Nov 2011]

ENSG00000138231 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000138231 DBR1 0.53 1.04e-11 HNSC
ENSG00000138231 DBR1 0.25 2.28e-11 BRCA
ENSG00000138231 DBR1 0.49 9.40e-11 LUSC
ENSG00000138231 DBR1 0.89 1.29e-12 GBM
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000138231 DBR1 cancer 28504715
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000138231 DBR1 MESO 0.025 low
ENSG00000138231 DBR1 SARC 0.045 high
ENSG00000138231 DBR1 STAD 0.031 low
ENSG00000138231 DBR1 UVM 0.002 low
ENSG00000138231 DBR1 UCEC 0.015 high
ENSG00000138231 DBR1 THCA 0.041 low
ENSG00000138231 DBR1 LUSC 0.0039 low
ENSG00000138231 DBR1 READ 0.018 low
ENSG00000138231 DBR1 KIRP 0.009 low
ENSG00000138231 DBR1 KICH 0.0044 high
ENSG00000138231 DBR1 PCPG 0.038 high
ENSG00000138231 DBR1 THYM 0.039 low
ENSG00000138231 DBR1 KIRC 0.00014 low
ENSG00000138231 DBR1 PRAD 0.0034 low
ENSG00000138231 DBR1 BLCA 0.045 low
ENSG00000138231 DBR1 SKCM 0.0024 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000138231 DBR1 LUSC Amp 10.105718 0.399791 0.763014 0.772455
ENSG00000138231 DBR1 CESC Amp 4.914903 0.260839 0.910466 0.671186
ENSG00000138231 DBR1 ESCA Amp 1.456839 0.307793 0.737365 0.543478
ENSG00000138231 DBR1 HNSC Amp 6.778009 0.231369 0.645115 0.618774
ENSG00000138231 DBR1 STAD Amp 0.895885 0.137187 0.478644 0.278912
ENSG00000138231 DBR1 PRAD Amp 3.092787 0.078302 0.472314 0.150407
ENSG00000138231 DBR1 UCEC Amp 0.829460 0.106184 0.584536 0.220779
ENSG00000138231 DBR1 OV Amp 6.493412 0.482017 0.775566 0.645941