Ensembl ID ENSG00000138095 Gene ID 10128 Accession 15714
Gene Symbol LRPPRC Alias LSFC;GP130;LRP130;MC4DN5;CLONE-23970 Full Name leucine rich pentatricopeptide repeat containing
Position 2 : 43886224 - 43996226 Length 110003 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq, Mar 2012]

ENSG00000138095 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000138095 LRPPRC -0.5 8.96e-16 KIRC
ENSG00000138095 LRPPRC 1.00 4.27e-35 LUSC
ENSG00000138095 LRPPRC 0.63 2.88e-18 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000138095 LRPPRC tumor 12762840
ENSG00000138095 LRPPRC cancer 15272088
ENSG00000138095 LRPPRC tumor 15590274
ENSG00000138095 LRPPRC tumor 19759419
ENSG00000138095 LRPPRC tumour 19851315
ENSG00000138095 LRPPRC cancers 22326293
ENSG00000138095 LRPPRC cancer 23153532
ENSG00000138095 LRPPRC cancers 23321674
ENSG00000138095 LRPPRC tumor 23635806
ENSG00000138095 LRPPRC cancer 24058810
ENSG00000138095 LRPPRC tumor 24168060
ENSG00000138095 LRPPRC gastric cancer 24375316
ENSG00000138095 LRPPRC prostate cancer 24390809
ENSG00000138095 LRPPRC cancers 24456369
ENSG00000138095 LRPPRC Cancer 24722279
ENSG00000138095 LRPPRC prostate cancer 25043940
ENSG00000138095 LRPPRC cancer 25074610
ENSG00000138095 LRPPRC prostate cancer 25379610
ENSG00000138095 LRPPRC tumor 25433944
ENSG00000138095 LRPPRC cancer 25961376
ENSG00000138095 LRPPRC endometrial cancer 26130650
ENSG00000138095 LRPPRC Cancer 26173622
ENSG00000138095 LRPPRC tumor 26209885
ENSG00000138095 LRPPRC cancer 26373715
ENSG00000138095 LRPPRC AML 26375984
ENSG00000138095 LRPPRC tumor 26571030
ENSG00000138095 LRPPRC cancer 26929249
ENSG00000138095 LRPPRC Prostate Cancer 27191117
ENSG00000138095 LRPPRC cancer 27474009
ENSG00000138095 LRPPRC Pancreatic Cancer 27535971
ENSG00000138095 LRPPRC metastatic prostate cancer 27679555
ENSG00000138095 LRPPRC cancer 27799870
ENSG00000138095 LRPPRC tumours 28000790
ENSG00000138095 LRPPRC cancer 28184026
ENSG00000138095 LRPPRC tumours 28186993
ENSG00000138095 LRPPRC tumors 28255813
ENSG00000138095 LRPPRC liver cancer 28430601
ENSG00000138095 LRPPRC colorectal cancer 28622966
ENSG00000138095 LRPPRC tumor 28626726
ENSG00000138095 LRPPRC cancer 28672024
ENSG00000138095 LRPPRC cancer 28711499
ENSG00000138095 LRPPRC tumor 29207075
ENSG00000138095 LRPPRC Pancreatic Cancer 29714141
ENSG00000138095 LRPPRC tumor 29777330
ENSG00000138095 LRPPRC lung cancer 30132982
ENSG00000138095 LRPPRC cancer 30190791
ENSG00000138095 LRPPRC tumor 30381445
ENSG00000138095 LRPPRC prostate cancer 30558204
ENSG00000138095 LRPPRC breast cancer 30563531
ENSG00000138095 LRPPRC liver tumor 30648776
ENSG00000138095 LRPPRC Colon Cancer 30736824
ENSG00000138095 LRPPRC triple-negative breast cancer 30852762
ENSG00000138095 LRPPRC lung cancer 30931929
ENSG00000138095 LRPPRC tumor 31053611
ENSG00000138095 LRPPRC cancer 31064115
ENSG00000138095 LRPPRC tumours 31091767
ENSG00000138095 LRPPRC tumors 31139333
ENSG00000138095 LRPPRC prostate cancer 31223111
ENSG00000138095 LRPPRC bladder cancer 31374291
ENSG00000138095 LRPPRC cancer 31546814
ENSG00000138095 LRPPRC tumor 31657561
ENSG00000138095 LRPPRC cancer 31765945
ENSG00000138095 LRPPRC tumor 31985234
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000138095 LRPPRC MESO 0.022 high
ENSG00000138095 LRPPRC SARC 0.031 high
ENSG00000138095 LRPPRC PAAD 0.00082 high
ENSG00000138095 LRPPRC ACC 0.0091 high
ENSG00000138095 LRPPRC LGG 0.00044 low
ENSG00000138095 LRPPRC LUSC 0.021 low
ENSG00000138095 LRPPRC HNSC 0.0068 high
ENSG00000138095 LRPPRC READ 0.0047 low
ENSG00000138095 LRPPRC KICH 0.035 high
ENSG00000138095 LRPPRC LUAD 0.0064 high
ENSG00000138095 LRPPRC PCPG 0.048 low
ENSG00000138095 LRPPRC COAD 0.021 low
ENSG00000138095 LRPPRC UCS 0.046 high
ENSG00000138095 LRPPRC ESCA 0.024 high
ENSG00000138095 LRPPRC PRAD 0.008 low
ENSG00000138095 LRPPRC BLCA 0.0099 high
ENSG00000138095 LRPPRC CESC 0.017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000138095 LRPPRC TGCT Amp 0.843213 0.123665 0.418512 0.386667