Ensembl ID
ENSG00000137996
Gene ID
8634
Accession
17981
Gene Symbol
RTCA
Alias
RPC;RTC1;RTCD1
Full Name
RNA 3'-terminal phosphate cyclase
Position
1 : 100266216 - 100292769
Length
26554 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs tRNA RBP type
Canonical_RBPs
Summary
This gene encodes a member of the RNA 3'-phosphate cyclase family. The encoded protein plays a role in RNA metabolism by catalyzing the ATP-dependent conversion of the 3'-phosphate of RNA substrates to a 2',3'-cyclic phosphodiester. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
ENSG00000137996 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000137996
RTCA
0.35
1.29e-14
BRCA
ENSG00000137996
RTCA
0.66
1.94e-23
UCEC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000137996
RTCA
tumors
1016941
ENSG00000137996
RTCA
AML
11758228
ENSG00000137996
RTCA
tumor
12571648
ENSG00000137996
RTCA
Cancer
12777147
ENSG00000137996
RTCA
tumors
15028961
ENSG00000137996
RTCA
cancer
18237428
ENSG00000137996
RTCA
tumor
2102659
ENSG00000137996
RTCA
tumor
21712475
ENSG00000137996
RTCA
tumor
2292455
ENSG00000137996
RTCA
tumor
2334133
ENSG00000137996
RTCA
pancreatic cancer
23369246
ENSG00000137996
RTCA
breast cancer
23457587
ENSG00000137996
RTCA
cancers
24310608
ENSG00000137996
RTCA
breast cancer
24425784
ENSG00000137996
RTCA
kidney tumors
24518236
ENSG00000137996
RTCA
breast cancer
24556279
ENSG00000137996
RTCA
esophageal cancer
24621512
ENSG00000137996
RTCA
tumor
24750242
ENSG00000137996
RTCA
Cancer
24885438
ENSG00000137996
RTCA
colon cancer
24935351
ENSG00000137996
RTCA
tumor
24949951
ENSG00000137996
RTCA
breast cancer
25329705
ENSG00000137996
RTCA
tumors
25474136
ENSG00000137996
RTCA
tumor
25907958
ENSG00000137996
RTCA
cancer
26329134
ENSG00000137996
RTCA
Rectal cancer
26437257
ENSG00000137996
RTCA
tumor
27029078
ENSG00000137996
RTCA
tumor
27424476
ENSG00000137996
RTCA
cancer
27518095
ENSG00000137996
RTCA
Tumor
28205557
ENSG00000137996
RTCA
gastric cancer
28359291
ENSG00000137996
RTCA
tumors
28388009
ENSG00000137996
RTCA
cancer
28626182
ENSG00000137996
RTCA
lung cancer
28960861
ENSG00000137996
RTCA
tumor
28962643
ENSG00000137996
RTCA
cancers
28974240
ENSG00000137996
RTCA
breast cancer
29018571
ENSG00000137996
RTCA
tumor
29020972
ENSG00000137996
RTCA
tumor
29467862
ENSG00000137996
RTCA
cancer
29629151
ENSG00000137996
RTCA
tumor
29970882
ENSG00000137996
RTCA
cancer
29983466
ENSG00000137996
RTCA
cancer
29983467
ENSG00000137996
RTCA
cancer
30134517
ENSG00000137996
RTCA
renal pelvis cancer
30214686
ENSG00000137996
RTCA
tumor
30500365
ENSG00000137996
RTCA
tumor
30774360
ENSG00000137996
RTCA
gastric cancer
31571995
ENSG00000137996
RTCA
tumor
31632267
ENSG00000137996
RTCA
plasma-cell tumor
5920197
ENSG00000137996
RTCA
tumor
59605
ENSG00000137996
RTCA
tumors
6551966
ENSG00000137996
RTCA
tumours
7464826
ENSG00000137996
RTCA
tumor
820372
ENSG00000137996
RTCA
tumor
8319246
ENSG00000137996
RTCA
tumor
8439986
ENSG00000137996
RTCA
tumor
850068
ENSG00000137996
RTCA
tumors
8640839
ENSG00000137996
RTCA
plasma cell tumours
974138
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000137996
RTCA
MESO
0.0037
high
show
ENSG00000137996
RTCA
SARC
0.00047
high
show
ENSG00000137996
RTCA
STAD
0.012
low
show
ENSG00000137996
RTCA
UVM
0.0047
high
show
ENSG00000137996
RTCA
PAAD
0.028
high
show
ENSG00000137996
RTCA
UCEC
0.029
low
show
ENSG00000137996
RTCA
LUSC
0.031
low
show
ENSG00000137996
RTCA
HNSC
0.042
high
show
ENSG00000137996
RTCA
KIRP
0.0016
high
show
ENSG00000137996
RTCA
LUAD
0.0031
high
show
ENSG00000137996
RTCA
BRCA
0.013
high
show
ENSG00000137996
RTCA
ESCA
0.041
high
show
ENSG00000137996
RTCA
OV
0.015
low
show
ENSG00000137996
RTCA
BLCA
0.039
high
show
ENSG00000137996
RTCA
GBM
0.022
high
show
ENSG00000137996
RTCA
SKCM
0.003
low
show
ENSG00000137996
RTCA
CESC
0.0073
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000137996
RTCA
LUSC
Del
3.113883
0.095299
0.376765
0.421158
ENSG00000137996
RTCA
LUAD
Del
9.054086
0.120644
0.346672
0.290698
ENSG00000137996
RTCA
CESC
Del
1.025950
0.073767
0.432066
0.101695
ENSG00000137996
RTCA
COAD
Del
4.033716
0.073457
0.424904
0.286031
ENSG00000137996
RTCA
ESCA
Del
0.735217
0.097674
0.381803
0.304348
ENSG00000137996
RTCA
SKCM
Del
3.098816
0.100890
0.426901
0.237057
ENSG00000137996
RTCA
HNSC
Del
3.309507
0.079643
0.362101
0.189655
ENSG00000137996
RTCA
PCPG
Del
17.161600
0.263311
0.689993
0.746914
ENSG00000137996
RTCA
BRCA
Del
7.743656
0.105558
0.395452
0.327778
ENSG00000137996
RTCA
STAD
Del
1.091937
0.066530
0.358086
0.204082
ENSG00000137996
RTCA
MESO
Del
9.848411
0.391994
0.575957
0.413793
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