Ensembl ID ENSG00000137513 Gene ID 79731 Accession 26274
Gene Symbol NARS2 Alias SLM5;asnRS;DFNB94 Full Name asparaginyl-tRNA synthetase 2, mitochondrial
Position 11 : 78435620 - 78575194 Length 139575 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of asparagine to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 24 (COXPD24). [provided by RefSeq, Mar 2015]

ENSG00000137513 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000137513 NARS2 -0.7 2.51e-38 KIRC
ENSG00000137513 NARS2 0.63 2.34e-14 COAD
ENSG00000137513 NARS2 -1.7 2.50e-30 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000137513 NARS2 cancer 31788113
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000137513 NARS2 MESO 0.047 high
ENSG00000137513 NARS2 SARC 0.00087 high
ENSG00000137513 NARS2 CHOL 0.0084 high
ENSG00000137513 NARS2 UVM 0.0053 low
ENSG00000137513 NARS2 UCEC 0.0013 high
ENSG00000137513 NARS2 THCA 0.036 low
ENSG00000137513 NARS2 ACC 0.042 high
ENSG00000137513 NARS2 LGG 0.0068 low
ENSG00000137513 NARS2 READ 0.0019 low
ENSG00000137513 NARS2 LUAD 0.03 low
ENSG00000137513 NARS2 THYM 0.029 low
ENSG00000137513 NARS2 COAD 0.0066 low
ENSG00000137513 NARS2 PRAD 0.025 low
ENSG00000137513 NARS2 LAML 0.0051 low
ENSG00000137513 NARS2 GBM 0.028 low
ENSG00000137513 NARS2 SKCM 0.00047 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000137513 NARS2 LUAD Amp 4.542586 0.196123 0.501030 0.319767
ENSG00000137513 NARS2 CESC Amp 1.550866 0.161646 0.672961 0.108475
ENSG00000137513 NARS2 SKCM Amp 7.944282 0.312307 0.927680 0.168937
ENSG00000137513 NARS2 HNSC Amp 8.585947 0.258426 0.663981 0.224138
ENSG00000137513 NARS2 BLCA Amp 3.161077 0.244000 0.681811 0.205882
ENSG00000137513 NARS2 BRCA Amp 48.720370 0.540890 1.093033 0.232407
ENSG00000137513 NARS2 STAD Amp 2.206358 0.175262 0.572331 0.222222
ENSG00000137513 NARS2 PRAD Amp 0.696352 0.045338 0.423835 0.091463
ENSG00000137513 NARS2 UCEC Amp 1.902474 0.131051 0.692242 0.100186
ENSG00000137513 NARS2 OV Amp 27.198722 0.787794 0.949718 0.433506