Ensembl ID ENSG00000136875 Gene ID 9128 Accession 17349
Gene Symbol PRPF4 Alias PRP4;RP70;HPRP4;Prp4p;HPRP4P;SNRNP60 Full Name pre-mRNA processing factor 4
Position 9 : 113275642 - 113294009 Length 18368 bases Strand Plus strand
Status Confidence Main interacting RNAssnRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]

ENSG00000136875 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000136875 PRPF4 0.62 5.69e-13 HNSC
ENSG00000136875 PRPF4 0.51 3.36e-28 BRCA
ENSG00000136875 PRPF4 0.83 1.43e-45 COAD
ENSG00000136875 PRPF4 0.83 1.05e-11 READ
ENSG00000136875 PRPF4 1.06 3.56e-29 LUSC
ENSG00000136875 PRPF4 0.49 3.28e-13 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000136875 PRPF4 AML 20514443
ENSG00000136875 PRPF4 breast cancer 31445970
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000136875 PRPF4 MESO 0.018 high
ENSG00000136875 PRPF4 SARC 0.0026 high
ENSG00000136875 PRPF4 UVM 0.017 high
ENSG00000136875 PRPF4 THCA 0.0013 high
ENSG00000136875 PRPF4 HNSC 0.0029 high
ENSG00000136875 PRPF4 READ 0.0015 low
ENSG00000136875 PRPF4 KIRP 0.00072 high
ENSG00000136875 PRPF4 KICH 0.00025 high
ENSG00000136875 PRPF4 LUAD 0.0046 high
ENSG00000136875 PRPF4 BRCA 0.032 high
ENSG00000136875 PRPF4 COAD 0.00022 high
ENSG00000136875 PRPF4 UCS 0.011 high
ENSG00000136875 PRPF4 OV 0.04 low
ENSG00000136875 PRPF4 BLCA 0.018 high
ENSG00000136875 PRPF4 SKCM 0.011 high
ENSG00000136875 PRPF4 LIHC 0.00065 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency