Ensembl ID ENSG00000136628 Gene ID 2058 Accession 3418
Gene Symbol EPRS1 Alias EARS;EPRS;PARS;QARS;QPRS;HLD15;PIG32;GLUPRORS Full Name glutamyl-prolyl-tRNA synthetase 1
Position 1 : 219968600 - 220046530 Length 77931 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined. [provided by RefSeq, Jul 2008]

ENSG00000136628 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000136628 EPRS1 0.79 1.21e-38 BRCA
ENSG00000136628 EPRS1 0.76 7.23e-23 LUSC
ENSG00000136628 EPRS1 0.76 1.54e-21 LIHC
ENSG00000136628 EPRS1 0.89 1.62e-35 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000136628 EPRS1 cancer 12384809
ENSG00000136628 EPRS1 cancer 24141779
ENSG00000136628 EPRS1 breast cancer 24510587
ENSG00000136628 EPRS1 cancers 26375396
ENSG00000136628 EPRS1 ER+ breast cancer 27612429
ENSG00000136628 EPRS1 tumor 27799870
ENSG00000136628 EPRS1 cancer 28631377
ENSG00000136628 EPRS1 cancer 29596499
ENSG00000136628 EPRS1 GBM 30572911
ENSG00000136628 EPRS1 breast cancer 31777591
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000136628 EPRS1 MESO 0.016 high
ENSG00000136628 EPRS1 SARC 0.015 high
ENSG00000136628 EPRS1 UCEC 0.02 low
ENSG00000136628 EPRS1 HNSC 0.013 high
ENSG00000136628 EPRS1 READ 0.021 low
ENSG00000136628 EPRS1 KICH 0.0011 high
ENSG00000136628 EPRS1 LUAD 0.024 high
ENSG00000136628 EPRS1 THYM 0.0034 high
ENSG00000136628 EPRS1 BRCA 0.0013 high
ENSG00000136628 EPRS1 DLBC 0.023 high
ENSG00000136628 EPRS1 PRAD 0.029 high
ENSG00000136628 EPRS1 BLCA 0.00075 high
ENSG00000136628 EPRS1 GBM 0.0016 low
ENSG00000136628 EPRS1 SKCM 0.038 high
ENSG00000136628 EPRS1 CESC 0.0079 high
ENSG00000136628 EPRS1 LIHC 0.0014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000136628 EPRS1 SARC Del 4.367685 0.205577 0.464580 0.319066
ENSG00000136628 EPRS1 GBM Del 1.467715 0.061544 0.464560 0.076256
ENSG00000136628 EPRS1 LIHC Amp 3.569993 0.179729 0.837281 0.729730
ENSG00000136628 EPRS1 BRCA Amp 8.463077 0.249755 0.785137 0.740741