Ensembl ID
ENSG00000135930
Gene ID
9470
Accession
3293
Gene Symbol
EIF4E2
Alias
4EHP;IF4e;4E-LP;h4EHP;EIF4EL3
Full Name
eukaryotic translation initiation factor 4E family member 2
Position
2 : 232550659 - 232583644
Length
32986 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
Enables ubiquitin protein ligase binding activity. Involved in positive regulation of miRNA mediated inhibition of translation. Acts upstream of or within negative regulation of translation. Located in P-body. Part of mRNA cap binding activity complex. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000135930 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000135930
EIF4E2
0.29
7.36e-14
BRCA
ENSG00000135930
EIF4E2
-0.8
1.00e-24
KICH
ENSG00000135930
EIF4E2
0.73
2.33e-19
UCEC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000135930
EIF4E2
MESO
0.0019
high
show
ENSG00000135930
EIF4E2
SARC
0.035
low
show
ENSG00000135930
EIF4E2
PAAD
0.014
high
show
ENSG00000135930
EIF4E2
UCEC
0.0034
low
show
ENSG00000135930
EIF4E2
LGG
0.031
high
show
ENSG00000135930
EIF4E2
READ
0.0012
high
show
ENSG00000135930
EIF4E2
KICH
0.0052
high
show
ENSG00000135930
EIF4E2
THYM
0.02
low
show
ENSG00000135930
EIF4E2
BRCA
0.033
high
show
ENSG00000135930
EIF4E2
COAD
0.048
high
show
ENSG00000135930
EIF4E2
OV
0.0094
low
show
ENSG00000135930
EIF4E2
DLBC
0.023
low
show
ENSG00000135930
EIF4E2
KIRC
0.0098
high
show
ENSG00000135930
EIF4E2
PRAD
0.042
high
show
ENSG00000135930
EIF4E2
TGCT
0.003
low
show
ENSG00000135930
EIF4E2
LAML
0.013
high
show
ENSG00000135930
EIF4E2
GBM
0.019
low
show
ENSG00000135930
EIF4E2
SKCM
0.013
low
show
ENSG00000135930
EIF4E2
LIHC
0.00035
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000135930
EIF4E2
LUSC
Del
18.098039
0.201619
0.391654
0.311377
ENSG00000135930
EIF4E2
LGG
Del
12.211409
0.116074
0.528089
0.122807
ENSG00000135930
EIF4E2
CESC
Del
40.180648
0.389020
0.537209
0.433898
ENSG00000135930
EIF4E2
KIRP
Amp
1.259300
0.069729
0.551282
0.152778
ENSG00000135930
EIF4E2
KIRP
Del
3.105280
0.049246
0.653407
0.041667
ENSG00000135930
EIF4E2
SARC
Del
15.827332
0.367343
0.625031
0.385214
ENSG00000135930
EIF4E2
ESCA
Del
3.151026
0.160632
0.392515
0.255435
ENSG00000135930
EIF4E2
SKCM
Del
4.063931
0.112100
0.450047
0.215259
ENSG00000135930
EIF4E2
HNSC
Del
22.691650
0.185419
0.380759
0.296935
ENSG00000135930
EIF4E2
BLCA
Del
33.542157
0.333286
0.458972
0.504902
ENSG00000135930
EIF4E2
BRCA
Del
5.344754
0.094431
0.358335
0.285185
ENSG00000135930
EIF4E2
STAD
Del
1.650358
0.074141
0.333315
0.140590
ENSG00000135930
EIF4E2
UCEC
Del
1.178093
0.054233
0.432912
0.083488
ENSG00000135930
EIF4E2
KIRC
Del
12.273903
0.074637
0.542790
0.089015
ENSG00000135930
EIF4E2
UVM
Del
1.063142
0.077139
0.955323
0.037500
ENSG00000135930
EIF4E2
OV
Del
2.568191
0.212416
0.492705
0.260794
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