Ensembl ID ENSG00000135870 Gene ID 149041 Accession 29434
Gene Symbol RC3H1 Alias FHL6;IMDSHY;RNF198;ROQUIN Full Name ring finger and CCCH-type domains 1
Position 1 : 173931084 - 174022357 Length 91274 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary This gene encodes a protein containing RING-type and C3H1-type zinc finger motifs. The encoded protein recognizes and binds to a constitutive decay element (CDE) in the 3' UTR of mRNAs, leading to mRNA deadenylation and degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

ENSG00000135870 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000135870 RC3H1 -0.4 1.78e-12 HNSC
ENSG00000135870 RC3H1 -0.4 2.24e-15 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000135870 RC3H1 tumors 22700722
ENSG00000135870 RC3H1 tumor 28512625
ENSG00000135870 RC3H1 cancers 29695787
ENSG00000135870 RC3H1 cancer 30650008
ENSG00000135870 RC3H1 tumors 31013298
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000135870 RC3H1 MESO 0.014 low
ENSG00000135870 RC3H1 PAAD 0.0099 low
ENSG00000135870 RC3H1 UCEC 0.033 high
ENSG00000135870 RC3H1 THCA 1e-04 high
ENSG00000135870 RC3H1 LGG 0.027 high
ENSG00000135870 RC3H1 HNSC 0.015 low
ENSG00000135870 RC3H1 READ 0.044 low
ENSG00000135870 RC3H1 LUAD 0.035 low
ENSG00000135870 RC3H1 BRCA 0.013 high
ENSG00000135870 RC3H1 UCS 0.027 low
ENSG00000135870 RC3H1 ESCA 0.0016 high
ENSG00000135870 RC3H1 OV 0.027 low
ENSG00000135870 RC3H1 KIRC 2e-04 low
ENSG00000135870 RC3H1 PRAD 0.0099 high
ENSG00000135870 RC3H1 BLCA 0.02 low
ENSG00000135870 RC3H1 CESC 0.049 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000135870 RC3H1 LUSC Amp 1.425645 0.218512 0.527962 0.508982
ENSG00000135870 RC3H1 LUAD Amp 1.851335 0.146133 0.507088 0.709302
ENSG00000135870 RC3H1 CESC Amp 0.703034 0.128074 0.608109 0.532203
ENSG00000135870 RC3H1 SARC Amp 3.564271 0.398481 0.760358 0.334630
ENSG00000135870 RC3H1 SKCM Amp 2.325503 0.170844 0.706126 0.534060
ENSG00000135870 RC3H1 LIHC Amp 8.209290 0.261505 0.878058 0.737838
ENSG00000135870 RC3H1 DLBC Amp 2.314444 0.347570 0.632214 0.312500
ENSG00000135870 RC3H1 BLCA Amp 6.643527 0.324764 0.575695 0.446078
ENSG00000135870 RC3H1 BRCA Amp 4.752784 0.208666 0.763198 0.736111
ENSG00000135870 RC3H1 UCEC Amp 1.846267 0.129812 0.822267 0.437848
ENSG00000135870 RC3H1 OV Amp 1.669079 0.363659 0.667598 0.549223