Ensembl ID ENSG00000135486 Gene ID 3178 Accession 5031
Gene Symbol HNRNPA1 Alias MPD3;UP1;ALS19;ALS20;HNRPA1;IBMPFD3;HNRPA1L3;hnRNPA1;hnRNP-A1 Full Name heterogeneous nuclear ribonucleoprotein A1
Position 12 : 54280193 - 54287088 Length 6896 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome. [provided by RefSeq, Feb 2016]

ENSG00000135486 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000135486 HNRNPA1 0.37 1.99e-19 KIRC
ENSG00000135486 HNRNPA1 0.67 1.99e-22 COAD
ENSG00000135486 HNRNPA1 0.45 6.08e-13 LUSC
ENSG00000135486 HNRNPA1 0.57 2.74e-13 LIHC
ENSG00000135486 HNRNPA1 1.07 9.79e-11 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000135486 HNRNPA1 lung cancer 12065097
ENSG00000135486 HNRNPA1 lung cancer 12871776
ENSG00000135486 HNRNPA1 cancer 15155834
ENSG00000135486 HNRNPA1 tumors 15390079
ENSG00000135486 HNRNPA1 colorectal cancers 15703818
ENSG00000135486 HNRNPA1 cancer 15734970
ENSG00000135486 HNRNPA1 prostate cancer 17110431
ENSG00000135486 HNRNPA1 cervical cancer 17869320
ENSG00000135486 HNRNPA1 renal cancer 19534619
ENSG00000135486 HNRNPA1 colorectal cancer 19715280
ENSG00000135486 HNRNPA1 cancer 20010808
ENSG00000135486 HNRNPA1 cancer 20133837
ENSG00000135486 HNRNPA1 cancer 20604928
ENSG00000135486 HNRNPA1 cancer 20639884
ENSG00000135486 HNRNPA1 tumour 20716340
ENSG00000135486 HNRNPA1 colorectal cancer 20872967
ENSG00000135486 HNRNPA1 tumor 21082031
ENSG00000135486 HNRNPA1 tumor 21194727
ENSG00000135486 HNRNPA1 cancer 22307054
ENSG00000135486 HNRNPA1 breast cancer 22345078
ENSG00000135486 HNRNPA1 cancer 22619672
ENSG00000135486 HNRNPA1 AML 22722453
ENSG00000135486 HNRNPA1 tumor 22821376
ENSG00000135486 HNRNPA1 liver cancer 23062008
ENSG00000135486 HNRNPA1 Non-Small Cell Lung Cancer 23658645
ENSG00000135486 HNRNPA1 cancer 23863836
ENSG00000135486 HNRNPA1 tumors 23921685
ENSG00000135486 HNRNPA1 tumor 23970380
ENSG00000135486 HNRNPA1 cancer 24065100
ENSG00000135486 HNRNPA1 tumor 24120475
ENSG00000135486 HNRNPA1 colon cancer 24166503
ENSG00000135486 HNRNPA1 liver cancer 24572810
ENSG00000135486 HNRNPA1 cancer 24720748
ENSG00000135486 HNRNPA1 tumor 24845017
ENSG00000135486 HNRNPA1 cancer 24962584
ENSG00000135486 HNRNPA1 tumour 25324306
ENSG00000135486 HNRNPA1 cancer 25752295
ENSG00000135486 HNRNPA1 pancreatic cancer 25799539
ENSG00000135486 HNRNPA1 Prostate Cancer 26056150
ENSG00000135486 HNRNPA1 breast cancer 26151392
ENSG00000135486 HNRNPA1 cancer 26273627
ENSG00000135486 HNRNPA1 colorectal cancer 26494299
ENSG00000135486 HNRNPA1 lung cancer 26581508
ENSG00000135486 HNRNPA1 pancreatic cancer 26616862
ENSG00000135486 HNRNPA1 bladder cancer 26674223
ENSG00000135486 HNRNPA1 tumor 26683771
ENSG00000135486 HNRNPA1 cancer 26728853
ENSG00000135486 HNRNPA1 gastric cancer 26745603
ENSG00000135486 HNRNPA1 breast cancer 26791953
ENSG00000135486 HNRNPA1 colon cancer 26825578
ENSG00000135486 HNRNPA1 tumor 26919236
ENSG00000135486 HNRNPA1 tumor 26930004
ENSG00000135486 HNRNPA1 cancer 26967561
ENSG00000135486 HNRNPA1 tumor 27248319
ENSG00000135486 HNRNPA1 colorectal cancer 27282379
ENSG00000135486 HNRNPA1 tumor 27303665
ENSG00000135486 HNRNPA1 tumor 27613566
ENSG00000135486 HNRNPA1 pancreatic cancer 27888145
ENSG00000135486 HNRNPA1 breast cancer 27935425
ENSG00000135486 HNRNPA1 cancer 27979648
ENSG00000135486 HNRNPA1 Cervical Cancer 27984373
ENSG00000135486 HNRNPA1 cancers 28035066
ENSG00000135486 HNRNPA1 cancer 28084329
ENSG00000135486 HNRNPA1 cancer 28086949
ENSG00000135486 HNRNPA1 cancers 28137272
ENSG00000135486 HNRNPA1 tumor 28147339
ENSG00000135486 HNRNPA1 cancer 28186082
ENSG00000135486 HNRNPA1 breast cancer 28315432
ENSG00000135486 HNRNPA1 GBM 28350847
ENSG00000135486 HNRNPA1 prostate cancer 28382513
ENSG00000135486 HNRNPA1 Tumor 28459042
ENSG00000135486 HNRNPA1 inflammatory myofibroblastic tumor of urinary bladder 28504207
ENSG00000135486 HNRNPA1 pancreatic cancer 28560430
ENSG00000135486 HNRNPA1 Prostate Cancer 28729398
ENSG00000135486 HNRNPA1 cancer 28791797
ENSG00000135486 HNRNPA1 GBM 28804724
ENSG00000135486 HNRNPA1 breast cancer 28881705
ENSG00000135486 HNRNPA1 cancer 28903433
ENSG00000135486 HNRNPA1 ovarian cancer 28904816
ENSG00000135486 HNRNPA1 cancers 29283381
ENSG00000135486 HNRNPA1 tumor 29288986
ENSG00000135486 HNRNPA1 lung cancer 29313979
ENSG00000135486 HNRNPA1 renal cancer 29331391
ENSG00000135486 HNRNPA1 colorectal cancer 29344170
ENSG00000135486 HNRNPA1 gastric cancer 29484423
ENSG00000135486 HNRNPA1 cancers 29495341
ENSG00000135486 HNRNPA1 cancers 29872500
ENSG00000135486 HNRNPA1 tumor 30127985
ENSG00000135486 HNRNPA1 tumor 30181816
ENSG00000135486 HNRNPA1 cancer 30210641
ENSG00000135486 HNRNPA1 tumors 30272759
ENSG00000135486 HNRNPA1 cancer 30279379
ENSG00000135486 HNRNPA1 cancer 30357359
ENSG00000135486 HNRNPA1 breast cancer 30368881
ENSG00000135486 HNRNPA1 tumor 30483132
ENSG00000135486 HNRNPA1 cancer 30548479
ENSG00000135486 HNRNPA1 Pancreatic Cancer 30577570
ENSG00000135486 HNRNPA1 tumor 30642385
ENSG00000135486 HNRNPA1 cancers 30731163
ENSG00000135486 HNRNPA1 cancer 30744200
ENSG00000135486 HNRNPA1 Prostate Cancer 30791548
ENSG00000135486 HNRNPA1 cancer 30857208
ENSG00000135486 HNRNPA1 tumor 30858544
ENSG00000135486 HNRNPA1 colorectal cancer 30954215
ENSG00000135486 HNRNPA1 colon cancer 31010097
ENSG00000135486 HNRNPA1 cancer 31257225
ENSG00000135486 HNRNPA1 cancers 31287951
ENSG00000135486 HNRNPA1 colon cancer 31311954
ENSG00000135486 HNRNPA1 prostate cancers 31366128
ENSG00000135486 HNRNPA1 pancreatic cancer 31480735
ENSG00000135486 HNRNPA1 tumors 31500199
ENSG00000135486 HNRNPA1 lung cancer 31501431
ENSG00000135486 HNRNPA1 tumor 31534508
ENSG00000135486 HNRNPA1 tumor 31666932
ENSG00000135486 HNRNPA1 tumors 9865741
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000135486 HNRNPA1 SARC 0.0023 high
ENSG00000135486 HNRNPA1 STAD 0.016 low
ENSG00000135486 HNRNPA1 CHOL 0.046 high
ENSG00000135486 HNRNPA1 UVM 0.0029 low
ENSG00000135486 HNRNPA1 PAAD 0.043 high
ENSG00000135486 HNRNPA1 UCEC 0.0031 low
ENSG00000135486 HNRNPA1 READ 0.00019 low
ENSG00000135486 HNRNPA1 KIRP 0.00025 high
ENSG00000135486 HNRNPA1 KICH 0.026 high
ENSG00000135486 HNRNPA1 LUAD 0.016 high
ENSG00000135486 HNRNPA1 PCPG 0.031 high
ENSG00000135486 HNRNPA1 THYM 0.0078 low
ENSG00000135486 HNRNPA1 BRCA 0.00075 low
ENSG00000135486 HNRNPA1 ESCA 0.039 high
ENSG00000135486 HNRNPA1 OV 0.049 low
ENSG00000135486 HNRNPA1 KIRC 0.017 low
ENSG00000135486 HNRNPA1 PRAD 0.023 high
ENSG00000135486 HNRNPA1 BLCA 0.0028 low
ENSG00000135486 HNRNPA1 LAML 0.032 low
ENSG00000135486 HNRNPA1 GBM 0.03 low
ENSG00000135486 HNRNPA1 LIHC 0.0018 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency