Ensembl ID ENSG00000135473 Gene ID 9924 Accession 20074
Gene Symbol PAN2 Alias USP52 Full Name poly(A) specific ribonuclease subunit PAN2
Position 12 : 56316223 - 56334053 Length 17831 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

ENSG00000135473 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000135473 PAN2 0.71 3.75e-18 KIRC
ENSG00000135473 PAN2 0.63 2.86e-12 COAD
ENSG00000135473 PAN2 -1.2 8.31e-12 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000135473 PAN2 renal cancer 23398456
ENSG00000135473 PAN2 breast cancer 29599486
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000135473 PAN2 MESO 0.024 low
ENSG00000135473 PAN2 PAAD 0.003 low
ENSG00000135473 PAN2 LGG 0.0066 high
ENSG00000135473 PAN2 HNSC 0.012 low
ENSG00000135473 PAN2 READ 0.031 low
ENSG00000135473 PAN2 KIRP 6e-04 low
ENSG00000135473 PAN2 KICH 0.00084 high
ENSG00000135473 PAN2 LUAD 0.0066 low
ENSG00000135473 PAN2 THYM 0.0043 low
ENSG00000135473 PAN2 COAD 0.0045 low
ENSG00000135473 PAN2 PRAD 0.023 high
ENSG00000135473 PAN2 BLCA 0.022 low
ENSG00000135473 PAN2 LAML 0.025 low
ENSG00000135473 PAN2 LIHC 0.027 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000135473 PAN2 ACC Amp 0.765694 0.253929 1.110787 0.766667
ENSG00000135473 PAN2 UCS Amp 0.823746 0.515751 0.629677 0.464286