Ensembl ID ENSG00000135269 Gene ID 26136 Accession 14620
Gene Symbol TES Alias TESS;TESS-2 Full Name testin LIM domain protein
Position 7 : 116210539 - 116258783 Length 48245 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a common fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Aug 2023]

ENSG00000135269 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000135269 -1.3 9.58e-13 BLCA
ENSG00000135269 -1.1 5.36e-40 PRAD
ENSG00000135269 1.17 4.28e-17 KIRP
ENSG00000135269 2.08 6.03e-21 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000135269 tumor 10403773
ENSG00000135269 tumor 10446453
ENSG00000135269 tumour 10584876
ENSG00000135269 tumor 10720474
ENSG00000135269 tumor 10723267
ENSG00000135269 tumors 10842193
ENSG00000135269 brain tumor 11051238
ENSG00000135269 tumor 11123432
ENSG00000135269 cancers 11248070
ENSG00000135269 tumours 11420696
ENSG00000135269 cancer 12032826
ENSG00000135269 tumours 12044516
ENSG00000135269 tumour 12571287
ENSG00000135269 tumor 12620387
ENSG00000135269 AML 12681366
ENSG00000135269 cancer 14579264
ENSG00000135269 tumour 14743347
ENSG00000135269 tumor 15252854
ENSG00000135269 tumour 15662727
ENSG00000135269 breast tumors 15701871
ENSG00000135269 cancer 16030183
ENSG00000135269 tumor 16033868
ENSG00000135269 tumor 16301813
ENSG00000135269 tumor 16353146
ENSG00000135269 tumor 1663921
ENSG00000135269 tumours 16734221
ENSG00000135269 tumor 16909125
ENSG00000135269 tumor 16929165
ENSG00000135269 epithelial ovarian cancer 16964386
ENSG00000135269 prostate cancer 17296370
ENSG00000135269 DLBCL 17608765
ENSG00000135269 tumour 17671631
ENSG00000135269 tumour 18454173
ENSG00000135269 tumor 18696217
ENSG00000135269 gastric cancer 18799041
ENSG00000135269 tumor 19096642
ENSG00000135269 cancer 19124256
ENSG00000135269 ovarian cancer 20180808
ENSG00000135269 breast cancer 20573277
ENSG00000135269 tumor 20622859
ENSG00000135269 tumor 20626849
ENSG00000135269 tumor 20876808
ENSG00000135269 tumor 21062507
ENSG00000135269 tumor 21318118
ENSG00000135269 Colon cancer 21887344
ENSG00000135269 tumours 22101996
ENSG00000135269 cancer 22651134
ENSG00000135269 breast cancer 22957844
ENSG00000135269 tumor 23248772
ENSG00000135269 tumor 23248773
ENSG00000135269 GBM 23512659
ENSG00000135269 breast cancer 23715752
ENSG00000135269 tumor 23734222
ENSG00000135269 tumor 23956979
ENSG00000135269 Tumor 24000984
ENSG00000135269 colorectal cancer 24294369
ENSG00000135269 tumors 24650279
ENSG00000135269 tumors 24893004
ENSG00000135269 Tumor 25009621
ENSG00000135269 breast cancer 25119600
ENSG00000135269 tumors 25333299
ENSG00000135269 gastric cancer 25498217
ENSG00000135269 liver cancer 25673160
ENSG00000135269 tumour 25884933
ENSG00000135269 metastatic colorectal cancer 25903799
ENSG00000135269 tumor 26063370
ENSG00000135269 Cancer 26189257
ENSG00000135269 cancer 26339343
ENSG00000135269 tumor 26468877
ENSG00000135269 Cancer 26560127
ENSG00000135269 tumor 26924343
ENSG00000135269 cancer 26985820
ENSG00000135269 lung cancer 27066187
ENSG00000135269 Tumor 27317788
ENSG00000135269 colorectal cancer 27323777
ENSG00000135269 tumor 27373040
ENSG00000135269 tumor 27809537
ENSG00000135269 tumour 27899997
ENSG00000135269 non-small cell lung cancer 28000866
ENSG00000135269 tumors 28529561
ENSG00000135269 Tumor 28532493
ENSG00000135269 tumour 28542564
ENSG00000135269 tumor 29242535
ENSG00000135269 GBM 29259714
ENSG00000135269 tumor 29507648
ENSG00000135269 Tumor 29615012
ENSG00000135269 cancer 29771068
ENSG00000135269 cancer 29798126
ENSG00000135269 gastric cancer 30063986
ENSG00000135269 tumor 3009372
ENSG00000135269 Tumor 30123044
ENSG00000135269 Tumor 30210254
ENSG00000135269 Cancers 30357755
ENSG00000135269 Tumor 30505419
ENSG00000135269 Ovarian cancer 30609934
ENSG00000135269 tumor 30728082
ENSG00000135269 breast cancer 30755730
ENSG00000135269 tumor 30867030
ENSG00000135269 Metastatic Colorectal Cancer 31390590
ENSG00000135269 tumor 7759859
ENSG00000135269 tumor 9240467
ENSG00000135269 tumors 9369931
ENSG00000135269 tumor 9679759
ENSG00000135269 tumors 9770241
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000135269 MESO 0.0051 high
ENSG00000135269 SARC 0.013 low
ENSG00000135269 UVM 0.0018 low
ENSG00000135269 THCA 0.007 high
ENSG00000135269 ACC 0.028 low
ENSG00000135269 LUSC 0.0029 high
ENSG00000135269 HNSC 0.0072 high
ENSG00000135269 KIRP 0.027 low
ENSG00000135269 KICH 0.022 high
ENSG00000135269 PCPG 0.028 low
ENSG00000135269 THYM 0.041 low
ENSG00000135269 COAD 0.0058 low
ENSG00000135269 ESCA 0.024 low
ENSG00000135269 OV 0.0039 low
ENSG00000135269 KIRC 0.00034 low
ENSG00000135269 PRAD 0.0072 high
ENSG00000135269 TGCT 0.048 high
ENSG00000135269 CESC 0.0062 high
ENSG00000135269 LIHC 0.00035 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000135269 LUAD Amp 1.996953 0.149194 0.482855 0.422481
ENSG00000135269 LGG Amp 4.231836 0.090705 0.664474 0.333333
ENSG00000135269 KIRP Amp 3.818739 0.140393 0.967756 0.611111
ENSG00000135269 ESCA Del 2.834588 0.153572 0.376184 0.271739
ENSG00000135269 SKCM Amp 0.846012 0.124534 0.670263 0.572207
ENSG00000135269 HNSC Del 1.994879 0.068236 0.364842 0.159004
ENSG00000135269 LIHC Amp 1.708906 0.139637 0.648551 0.321622
ENSG00000135269 STAD Amp 1.301554 0.150256 0.519940 0.378685