Ensembl ID
ENSG00000134698
Gene ID
192670
Accession
18424
Gene Symbol
AGO4
Alias
EIF2C4
Full Name
argonaute RISC component 4
Position
1 : 35808016 - 35857890
Length
49875 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs ncRNA RBP type
Canonical_RBPs
Summary
This gene encodes a member of the Argonaute family of proteins which contain PAZ and PIWI domains and play an integral role in RNA interference and short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a cluster of related family members. [provided by RefSeq, Mar 2017]
ENSG00000134698 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000134698
AGO4
0.39
7.97e-12
KIRC
ENSG00000134698
AGO4
-0.5
1.19e-24
BRCA
ENSG00000134698
AGO4
-0.6
1.29e-15
LUSC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000134698
AGO4
cancer
20146808
ENSG00000134698
AGO4
tumors
27518285
ENSG00000134698
AGO4
gastric cancer
29719612
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000134698
AGO4
STAD
0.0064
high
show
ENSG00000134698
AGO4
CHOL
0.033
low
show
ENSG00000134698
AGO4
ACC
0.0012
high
show
ENSG00000134698
AGO4
READ
0.0044
low
show
ENSG00000134698
AGO4
KICH
0.016
high
show
ENSG00000134698
AGO4
LUAD
0.00059
low
show
ENSG00000134698
AGO4
BRCA
0.017
high
show
ENSG00000134698
AGO4
OV
0.014
high
show
ENSG00000134698
AGO4
PRAD
0.00017
low
show
ENSG00000134698
AGO4
BLCA
0.03
low
show
ENSG00000134698
AGO4
LAML
0.0079
low
show
ENSG00000134698
AGO4
SKCM
0.0098
low
show
ENSG00000134698
AGO4
LIHC
0.007
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000134698
AGO4
CHOL
Del
5.636130
0.511251
0.614260
0.472222
ENSG00000134698
AGO4
KIRP
Del
2.873165
0.047366
0.589190
0.156250
ENSG00000134698
AGO4
COAD
Del
1.811992
0.054253
0.403964
0.279379
ENSG00000134698
AGO4
LIHC
Del
5.279578
0.124358
0.514240
0.316216
ENSG00000134698
AGO4
PCPG
Del
1.352336
0.072177
0.671612
0.617284
ENSG00000134698
AGO4
BRCA
Del
1.731714
0.072578
0.382982
0.309259
ENSG00000134698
AGO4
UCEC
Del
0.639988
0.046600
0.425594
0.077922
ENSG00000134698
AGO4
KIRC
Del
1.481253
0.029732
0.418665
0.157197
ENSG00000134698
AGO4
UVM
Del
1.628635
0.094732
0.808745
0.300000
ENSG00000134698
AGO4
OV
Amp
7.119600
0.494176
0.696860
0.426598
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.