tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Position
2 : 9583967 - 9630997
Length
47031 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs
N.A.
RBP type
Non-canonical_RBPs
Summary
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]