Ensembl ID ENSG00000134308 Gene ID 10971 Accession 12854
Gene Symbol YWHAQ Alias 1C5;HS1;14-3-3 Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
Position 2 : 9583967 - 9630997 Length 47031 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]

ENSG00000134308 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000134308 YWHAQ -0.8 4.51e-13 KICH
ENSG00000134308 YWHAQ 0.90 3.96e-23 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000134308 YWHAQ prostate cancer 19893039
ENSG00000134308 YWHAQ tumors 29487377
ENSG00000134308 YWHAQ tumor 31188160
ENSG00000134308 YWHAQ tumours 31892336
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000134308 YWHAQ SARC 0.00042 high
ENSG00000134308 YWHAQ STAD 0.042 high
ENSG00000134308 YWHAQ UVM 0.03 high
ENSG00000134308 YWHAQ UCEC 0.00055 low
ENSG00000134308 YWHAQ ACC 0.00055 high
ENSG00000134308 YWHAQ HNSC 0.0046 high
ENSG00000134308 YWHAQ READ 0.047 low
ENSG00000134308 YWHAQ KICH 0.00037 high
ENSG00000134308 YWHAQ LUAD 0.0026 high
ENSG00000134308 YWHAQ THYM 0.036 low
ENSG00000134308 YWHAQ BRCA 0.028 high
ENSG00000134308 YWHAQ UCS 0.011 low
ENSG00000134308 YWHAQ DLBC 0.033 low
ENSG00000134308 YWHAQ PRAD 0.0053 high
ENSG00000134308 YWHAQ BLCA 0.0029 high
ENSG00000134308 YWHAQ SKCM 0.029 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000134308 YWHAQ LIHC Amp 1.060797 0.122360 0.512059 0.172973
ENSG00000134308 YWHAQ TGCT Amp 1.690985 0.162419 0.462090 0.380000
ENSG00000134308 YWHAQ BLCA Amp 0.918829 0.172261 0.513048 0.365196
ENSG00000134308 YWHAQ UCEC Amp 1.492080 0.122248 0.602958 0.215213