Ensembl ID ENSG00000134056 Gene ID 92259 Accession 16631
Gene Symbol MRPS36 Alias DC47;MRP-S36 Full Name mitochondrial ribosomal protein S36
Position 5 : 69217760 - 69230158 Length 12399 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Non-canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. [provided by RefSeq, Jul 2008]

ENSG00000134056 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000134056 MRPS36 -0.6 1.24e-12 HNSC
ENSG00000134056 MRPS36 -0.6 3.43e-11 COAD
ENSG00000134056 MRPS36 -0.6 2.66e-11 LUSC
ENSG00000134056 MRPS36 -0.8 2.96e-13 STAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000134056 MRPS36 MESO 0.0045 low
ENSG00000134056 MRPS36 SARC 0.00049 low
ENSG00000134056 MRPS36 UVM 0.0062 high
ENSG00000134056 MRPS36 PAAD 0.027 low
ENSG00000134056 MRPS36 THCA 0.013 low
ENSG00000134056 MRPS36 HNSC 0.0027 high
ENSG00000134056 MRPS36 KIRP 0.0084 low
ENSG00000134056 MRPS36 KICH 0.012 high
ENSG00000134056 MRPS36 COAD 0.026 low
ENSG00000134056 MRPS36 UCS 0.0056 high
ENSG00000134056 MRPS36 OV 0.0048 low
ENSG00000134056 MRPS36 SKCM 0.0031 low
ENSG00000134056 MRPS36 CESC 0.0043 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000134056 MRPS36 LUSC Del 3.211697 0.096380 0.406379 0.764471
ENSG00000134056 MRPS36 LUAD Del 3.223916 0.078891 0.344779 0.385659
ENSG00000134056 MRPS36 CESC Del 0.647755 0.065326 0.457445 0.247458
ENSG00000134056 MRPS36 READ Del 1.472365 0.092517 0.451869 0.339394
ENSG00000134056 MRPS36 COAD Del 3.291368 0.067696 0.391534 0.243902
ENSG00000134056 MRPS36 UCS Del 2.613906 0.346061 0.512911 0.517857
ENSG00000134056 MRPS36 PAAD Del 1.959888 0.070019 0.347389 0.179348
ENSG00000134056 MRPS36 ESCA Del 2.905291 0.155337 0.440464 0.619565
ENSG00000134056 MRPS36 HNSC Del 2.886892 0.076325 0.387063 0.411877
ENSG00000134056 MRPS36 BLCA Del 6.896519 0.152579 0.419469 0.509804
ENSG00000134056 MRPS36 BRCA Del 7.268796 0.103453 0.455543 0.268519
ENSG00000134056 MRPS36 STAD Del 9.096065 0.139689 0.394301 0.383220
ENSG00000134056 MRPS36 PRAD Del 23.037663 0.218290 0.561307 0.199187
ENSG00000134056 MRPS36 UCEC Del 9.289947 0.115697 0.521339 0.205937
ENSG00000134056 MRPS36 OV Del 81.875141 0.718027 0.673463 0.725389