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Ensembl ID | ENSG00000133112 | Gene ID | 7178 | Accession | 12022 |
Gene Symbol | TPT1 | Alias | HRF;p02;p23;TCTP | Full Name | tumor protein, translationally-controlled 1 |
Position | 13 : 45333471 - 45341284 | Length | 7814 bases | Strand | Minus strand |
Status | Confidence | Main interacting RNAs | N.A. | RBP type | Non-canonical_RBPs |
Summary | This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017] |
ENSG00000133112 Expression In 33 Tumors
Ensembl ID | Gene symbol | Log2 Foldchange | Pvaue | Cancer |
---|---|---|---|---|
ENSG00000133112 | 0.64 | 2.27e-17 | KIRC | |
ENSG00000133112 | -1.0 | 2.74e-27 | HNSC | |
ENSG00000133112 | -0.5 | 2.25e-18 | BRCA | |
ENSG00000133112 | -0.7 | 6.66e-14 | LIHC |
Ensembl ID | Gene symbol | Cancer types | Pubmed ID |
---|---|---|---|
ENSG00000133112 | tumor | 10343127 | |
ENSG00000133112 | tumour | 10477280 | |
ENSG00000133112 | colon cancer | 10880768 | |
ENSG00000133112 | tumour | 10951206 | |
ENSG00000133112 | tumors | 10953283 | |
ENSG00000133112 | tumor | 11120605 | |
ENSG00000133112 | tumor | 11156187 | |
ENSG00000133112 | tumor | 11473261 | |
ENSG00000133112 | tumour | 11578093 | |
ENSG00000133112 | breast cancer | 11598139 | |
ENSG00000133112 | tumor | 12399545 | |
ENSG00000133112 | tumor | 12882707 | |
ENSG00000133112 | tumour | 12922171 | |
ENSG00000133112 | tumour | 12931192 | |
ENSG00000133112 | tumour | 14623943 | |
ENSG00000133112 | tumor | 14623968 | |
ENSG00000133112 | tumour | 14687915 | |
ENSG00000133112 | prostate cancer | 15162379 | |
ENSG00000133112 | tumors | 15364286 | |
ENSG00000133112 | tumor | 15489264 | |
ENSG00000133112 | tumor | 15598614 | |
ENSG00000133112 | tumor | 15878303 | |
ENSG00000133112 | tumour | 16006164 | |
ENSG00000133112 | tumors | 16193335 | |
ENSG00000133112 | tumour | 16236172 | |
ENSG00000133112 | tumor | 16638191 | |
ENSG00000133112 | breast cancer | 17127214 | |
ENSG00000133112 | cancer | 17201911 | |
ENSG00000133112 | tumour | 17301792 | |
ENSG00000133112 | prostate cancer | 17549383 | |
ENSG00000133112 | tumor | 17579559 | |
ENSG00000133112 | cancer | 18274553 | |
ENSG00000133112 | tumour | 18298087 | |
ENSG00000133112 | cancers | 18325342 | |
ENSG00000133112 | tumor | 18617898 | |
ENSG00000133112 | cancer | 18630514 | |
ENSG00000133112 | tumour | 18692051 | |
ENSG00000133112 | tumour | 18938170 | |
ENSG00000133112 | tumor | 19114010 | |
ENSG00000133112 | lung cancer | 19116456 | |
ENSG00000133112 | cancer | 19168579 | |
ENSG00000133112 | tumour | 19180095 | |
ENSG00000133112 | cancer | 19262129 | |
ENSG00000133112 | tumour | 19285501 | |
ENSG00000133112 | tumors | 19360299 | |
ENSG00000133112 | prostate cancer | 19360337 | |
ENSG00000133112 | cancer | 19364479 | |
ENSG00000133112 | cancer | 19397818 | |
ENSG00000133112 | tumor | 19558675 | |
ENSG00000133112 | tumor | 19621893 | |
ENSG00000133112 | tumour | 19815065 | |
ENSG00000133112 | tumour | 19901967 | |
ENSG00000133112 | tumor | 20230689 | |
ENSG00000133112 | tumour | 20336009 | |
ENSG00000133112 | tumors | 20552026 | |
ENSG00000133112 | tumor | 20795647 | |
ENSG00000133112 | tumour | 20838377 | |
ENSG00000133112 | Tumor | 20966960 | |
ENSG00000133112 | tumor | 21036172 | |
ENSG00000133112 | tumour | 21063673 | |
ENSG00000133112 | lung cancer | 21081126 | |
ENSG00000133112 | cancer | 21136954 | |
ENSG00000133112 | tumour | 21187478 | |
ENSG00000133112 | tumor | 21278788 | |
ENSG00000133112 | tumor | 21304173 | |
ENSG00000133112 | colorectal cancer | 21466289 | |
ENSG00000133112 | breast cancer | 21478820 | |
ENSG00000133112 | tumor | 21549610 | |
ENSG00000133112 | cancer | 21565400 | |
ENSG00000133112 | tumor | 21637603 | |
ENSG00000133112 | tumour | 21728753 | |
ENSG00000133112 | breast cancer | 21730980 | |
ENSG00000133112 | tumor | 21795694 | |
ENSG00000133112 | cancer | 21801721 | |
ENSG00000133112 | breast cancer | 21945766 | |
ENSG00000133112 | tumor | 21953552 | |
ENSG00000133112 | tumour | 22069711 | |
ENSG00000133112 | cancer | 22079950 | |
ENSG00000133112 | tumour | 22125622 | |
ENSG00000133112 | tumor | 22157679 | |
ENSG00000133112 | tumour | 22311416 | |
ENSG00000133112 | colon cancer | 22340241 | |
ENSG00000133112 | tumor | 22428011 | |
ENSG00000133112 | cancer of the gastric cardia | 22468085 | |
ENSG00000133112 | tumour | 22503395 | |
ENSG00000133112 | cancer | 22567286 | |
ENSG00000133112 | cancer | 22570787 | |
ENSG00000133112 | Cancer | 22649730 | |
ENSG00000133112 | Tumour | 22655198 | |
ENSG00000133112 | Cancer | 22666592 | |
ENSG00000133112 | cancer | 22675633 | |
ENSG00000133112 | cancer | 22761999 | |
ENSG00000133112 | tumour | 22853445 | |
ENSG00000133112 | prostate cancer | 22893039 | |
ENSG00000133112 | oral cancer | 22902387 | |
ENSG00000133112 | Tumour | 22912717 | |
ENSG00000133112 | tumor | 22969908 | |
ENSG00000133112 | ovarian cancer | 23042265 | |
ENSG00000133112 | tumors | 23055753 | |
ENSG00000133112 | cancer | 23122550 | |
ENSG00000133112 | breast cancer | 23165143 | |
ENSG00000133112 | colorectal cancer | 23203071 | |
ENSG00000133112 | ovarian cancer | 23323103 | |
ENSG00000133112 | pancreatic cancer | 23358553 | |
ENSG00000133112 | tumour | 23387829 | |
ENSG00000133112 | tumor | 23434429 | |
ENSG00000133112 | tumour | 23520509 | |
ENSG00000133112 | tumor | 23749504 | |
ENSG00000133112 | Prostate Cancer | 23894469 | |
ENSG00000133112 | tumor | 24004562 | |
ENSG00000133112 | Tumour | 24040826 | |
ENSG00000133112 | Tumor | 24122620 | |
ENSG00000133112 | tumour | 24124757 | |
ENSG00000133112 | pancreatic cancer | 24165482 | |
ENSG00000133112 | tumor | 24248465 | |
ENSG00000133112 | tumour | 24280521 | |
ENSG00000133112 | tumor | 24311645 | |
ENSG00000133112 | tumour | 24329985 | |
ENSG00000133112 | cancer | 24352200 | |
ENSG00000133112 | tumor | 24359616 | |
ENSG00000133112 | tumor | 24402820 | |
ENSG00000133112 | cancer | 24606760 | |
ENSG00000133112 | cancers | 24650927 | |
ENSG00000133112 | tumor | 24657995 | |
ENSG00000133112 | lung cancer | 24761856 | |
ENSG00000133112 | tumors | 25092287 | |
ENSG00000133112 | cancers | 25211298 | |
ENSG00000133112 | cancer | 25245035 | |
ENSG00000133112 | DLBCL | 25363345 | |
ENSG00000133112 | tumour | 25376500 | |
ENSG00000133112 | tumor | 25396429 | |
ENSG00000133112 | lung cancer | 25423047 | |
ENSG00000133112 | tumor | 25487856 | |
ENSG00000133112 | tumor | 25494248 | |
ENSG00000133112 | cancer | 25558447 | |
ENSG00000133112 | epithelial ovarian cancer | 25564355 | |
ENSG00000133112 | colon cancer | 25622969 | |
ENSG00000133112 | tumor | 25667934 | |
ENSG00000133112 | breast cancer | 25779659 | |
ENSG00000133112 | tumour | 25936523 | |
ENSG00000133112 | tumour | 26011413 | |
ENSG00000133112 | tumour | 26290464 | |
ENSG00000133112 | tumor | 26328748 | |
ENSG00000133112 | tumor | 26425551 | |
ENSG00000133112 | gastric cancer | 26499154 | |
ENSG00000133112 | tumour | 26808010 | |
ENSG00000133112 | cancer | 26813996 | |
ENSG00000133112 | cervical cancer | 26854447 | |
ENSG00000133112 | breast cancers | 26903505 | |
ENSG00000133112 | cancer | 26921194 | |
ENSG00000133112 | tumor | 26972431 | |
ENSG00000133112 | tumour | 27159273 | |
ENSG00000133112 | colorectal cancer | 27367023 | |
ENSG00000133112 | tumor | 27382303 | |
ENSG00000133112 | breast cancer | 27416835 | |
ENSG00000133112 | Cancer | 27607350 | |
ENSG00000133112 | cancers | 27687497 | |
ENSG00000133112 | tumor | 27764782 | |
ENSG00000133112 | tumor | 27783042 | |
ENSG00000133112 | cancer | 27813490 | |
ENSG00000133112 | tumour | 27917920 | |
ENSG00000133112 | lung cancers | 28128835 | |
ENSG00000133112 | colon cancer | 28143584 | |
ENSG00000133112 | tumour | 28403226 | |
ENSG00000133112 | tumor | 28409693 | |
ENSG00000133112 | prostate cancer | 28472637 | |
ENSG00000133112 | tumor | 28506239 | |
ENSG00000133112 | cancers | 28536478 | |
ENSG00000133112 | tumor | 28550308 | |
ENSG00000133112 | tumour | 28751755 | |
ENSG00000133112 | cancer | 28846114 | |
ENSG00000133112 | tumour | 28855394 | |
ENSG00000133112 | tumor | 28923001 | |
ENSG00000133112 | Pancreatic Cancer | 28928875 | |
ENSG00000133112 | cancers | 28939212 | |
ENSG00000133112 | cancer | 28958626 | |
ENSG00000133112 | tumor | 28969635 | |
ENSG00000133112 | lung cancer | 28970113 | |
ENSG00000133112 | tumor | 29113234 | |
ENSG00000133112 | cancer | 29149401 | |
ENSG00000133112 | Tumour | 29149404 | |
ENSG00000133112 | tumor | 29149405 | |
ENSG00000133112 | cancer | 29149408 | |
ENSG00000133112 | Tumor | 29149411 | |
ENSG00000133112 | Prostate Cancer | 29149413 | |
ENSG00000133112 | Cancer | 29149414 | |
ENSG00000133112 | Cancer | 29149415 | |
ENSG00000133112 | cancer | 29216544 | |
ENSG00000133112 | lung cancer | 29254214 | |
ENSG00000133112 | cancer | 29317542 | |
ENSG00000133112 | tumour | 29324689 | |
ENSG00000133112 | tumor | 29385181 | |
ENSG00000133112 | cancer | 29867020 | |
ENSG00000133112 | tumor | 30009039 | |
ENSG00000133112 | GBM | 30029885 | |
ENSG00000133112 | tumor | 30045766 | |
ENSG00000133112 | tumors | 30066846 | |
ENSG00000133112 | Tumor | 30370446 | |
ENSG00000133112 | Tumor | 30381327 | |
ENSG00000133112 | colorectal cancer | 30563768 | |
ENSG00000133112 | cancer | 30695029 | |
ENSG00000133112 | Tumor | 30721952 | |
ENSG00000133112 | lung cancer | 30763986 | |
ENSG00000133112 | cancer | 30764831 | |
ENSG00000133112 | lung cancer | 30805558 | |
ENSG00000133112 | breast cancer | 30815593 | |
ENSG00000133112 | tumor | 30881019 | |
ENSG00000133112 | tumor | 30893896 | |
ENSG00000133112 | tumor | 30941821 | |
ENSG00000133112 | tumor | 31015543 | |
ENSG00000133112 | tumor | 31015848 | |
ENSG00000133112 | tumour | 31037291 | |
ENSG00000133112 | tumor | 31052313 | |
ENSG00000133112 | cervical cancer | 31124937 | |
ENSG00000133112 | tumor | 31146137 | |
ENSG00000133112 | tumour | 31249193 | |
ENSG00000133112 | prostate cancer | 31295912 | |
ENSG00000133112 | cancer | 31320615 | |
ENSG00000133112 | tumor | 31637705 | |
ENSG00000133112 | tumor | 31715683 | |
ENSG00000133112 | cancer | 31749945 | |
ENSG00000133112 | cancer | 31788113 | |
ENSG00000133112 | tumor | 31885695 | |
ENSG00000133112 | tumor | 31935927 | |
ENSG00000133112 | tumor | 31938365 | |
ENSG00000133112 | cancer | 31968668 | |
ENSG00000133112 | tumour | 9655922 | |
ENSG00000133112 | metastatic prostate cancer | 9778121 |
Ensembl ID | Gene symbol | Disease/phenotype | Mutation type | Mutated / Total samples | Literature |
---|
Ensembl ID | Gene symbol | Cancer | P-value | Which worse | show |
---|---|---|---|---|---|
ENSG00000133112 | MESO | 0.0054 | low | ||
ENSG00000133112 | UCEC | 0.00028 | high | ||
ENSG00000133112 | LGG | 0.00016 | low | ||
ENSG00000133112 | HNSC | 0.025 | high | ||
ENSG00000133112 | READ | 0.02 | high | ||
ENSG00000133112 | KIRP | 0.014 | high | ||
ENSG00000133112 | KICH | 0.026 | high | ||
ENSG00000133112 | ESCA | 0.011 | high | ||
ENSG00000133112 | OV | 0.0043 | high | ||
ENSG00000133112 | KIRC | 0.041 | high | ||
ENSG00000133112 | LAML | 0.013 | low | ||
ENSG00000133112 | SKCM | 0.01 | low | ||
ENSG00000133112 | LIHC | 0.0039 | low |
Ensembl ID | Gene symbol | Cancer | CNV type | -log10(q-value) | G-score | average amplitude | frequency |
---|---|---|---|---|---|---|---|
ENSG00000133112 | LUSC | Del | 4.163186 | 0.105456 | 0.383441 | 0.686627 | |
ENSG00000133112 | LUAD | Del | 1.757268 | 0.064623 | 0.327561 | 0.554264 | |
ENSG00000133112 | LGG | Del | 3.512221 | 0.064579 | 0.448168 | 0.272904 | |
ENSG00000133112 | CESC | Del | 16.693686 | 0.229742 | 0.499782 | 0.389831 | |
ENSG00000133112 | READ | Amp | 0.728557 | 0.124766 | 1.040186 | 0.690909 | |
ENSG00000133112 | COAD | Amp | 5.554578 | 0.149234 | 0.906225 | 0.587583 | |
ENSG00000133112 | SARC | Del | 14.988214 | 0.356811 | 0.624056 | 0.645914 | |
ENSG00000133112 | GBM | Del | 10.093160 | 0.125903 | 0.581849 | 0.396880 | |
ENSG00000133112 | THCA | Del | 1.458287 | 0.012584 | 0.589039 | 0.036072 | |
ENSG00000133112 | HNSC | Del | 12.585642 | 0.135228 | 0.409596 | 0.419540 | |
ENSG00000133112 | LIHC | Del | 23.831295 | 0.260714 | 0.609658 | 0.472973 | |
ENSG00000133112 | BLCA | Del | 17.971474 | 0.236166 | 0.461476 | 0.338235 | |
ENSG00000133112 | BRCA | Del | 15.216583 | 0.133427 | 0.492656 | 0.458333 | |
ENSG00000133112 | PRAD | Del | 71.024463 | 0.405554 | 0.550752 | 0.457317 | |
ENSG00000133112 | UCEC | Del | 1.246450 | 0.055036 | 0.536740 | 0.194805 | |
ENSG00000133112 | MESO | Del | 1.544449 | 0.158042 | 0.474374 | 0.482759 | |
ENSG00000133112 | KIRC | Del | 0.746692 | 0.024811 | 0.355168 | 0.153409 | |
ENSG00000133112 | OV | Del | 4.014510 | 0.233920 | 0.623868 | 0.626943 |