Ensembl ID ENSG00000132661 Gene ID 29107 Accession 15913
Gene Symbol NXT1 Alias P15;MTR2 Full Name nuclear transport factor 2 like export factor 1
Position 20 : 23350791 - 23354771 Length 3981 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000132661 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000132661 NXT1 0.56 5.49e-18 BRCA
ENSG00000132661 NXT1 1.42 6.43e-27 COAD
ENSG00000132661 NXT1 0.77 5.55e-15 LUSC
ENSG00000132661 NXT1 2.38 3.29e-14 GBM
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000132661 NXT1 tumor 6157835
ENSG00000132661 NXT1 tumors 7547637
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000132661 NXT1 UVM 0.0061 high
ENSG00000132661 NXT1 UCEC 0.0012 high
ENSG00000132661 NXT1 THCA 0.007 high
ENSG00000132661 NXT1 ACC 0.022 high
ENSG00000132661 NXT1 HNSC 0.026 high
ENSG00000132661 NXT1 READ 0.0086 low
ENSG00000132661 NXT1 KIRP 0.00075 high
ENSG00000132661 NXT1 KICH 0.004 low
ENSG00000132661 NXT1 BRCA 0.048 low
ENSG00000132661 NXT1 ESCA 0.011 high
ENSG00000132661 NXT1 DLBC 0.027 low
ENSG00000132661 NXT1 PRAD 0.05 low
ENSG00000132661 NXT1 LIHC 0.00032 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000132661 NXT1 READ Amp 1.165134 0.149262 0.955865 0.636364
ENSG00000132661 NXT1 COAD Amp 4.316307 0.129941 0.935681 0.523282