Ensembl ID ENSG00000132591 Gene ID 26284 Accession 3424
Gene Symbol ERAL1 Alias ERA;CEGA;ERA-W;H-ERA;ERAL1A;ERAL1B;HERA-A;HERA-B;PRLTS6 Full Name Era like 12S mitochondrial rRNA chaperone 1
Position 17 : 28855010 - 28861061 Length 6052 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

ENSG00000132591 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000132591 ERAL1 0.64 4.67e-24 BRCA
ENSG00000132591 ERAL1 0.83 1.36e-29 LUSC
ENSG00000132591 ERAL1 0.75 5.42e-18 UCEC
ENSG00000132591 ERAL1 0.61 3.61e-19 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000132591 ERAL1 tumor 10945472
ENSG00000132591 ERAL1 breast cancer 18390416
ENSG00000132591 ERAL1 tumor 18665746
ENSG00000132591 ERAL1 breast cancer 21504237
ENSG00000132591 ERAL1 Breast Cancer 21695277
ENSG00000132591 ERAL1 Breast Cancer 22215751
ENSG00000132591 ERAL1 breast cancer 22367645
ENSG00000132591 ERAL1 tumor 22576012
ENSG00000132591 ERAL1 breast cancer 23328596
ENSG00000132591 ERAL1 breast cancer 23414588
ENSG00000132591 ERAL1 Breast Cancer 25400908
ENSG00000132591 ERAL1 tumors 25939896
ENSG00000132591 ERAL1 Cancer 28379421
ENSG00000132591 ERAL1 breast cancer 29530933
ENSG00000132591 ERAL1 colorectal cancer 30273198
ENSG00000132591 ERAL1 tumor 30298117
ENSG00000132591 ERAL1 tumor 30400822
ENSG00000132591 ERAL1 breast cancer 30506110
ENSG00000132591 ERAL1 Breast Cancer 30711959
ENSG00000132591 ERAL1 tumor 31324216
ENSG00000132591 ERAL1 Cancer 31492560
ENSG00000132591 ERAL1 Breast Cancer 31654782
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000132591 ERAL1 MESO 0.05 high
ENSG00000132591 ERAL1 SARC 0.022 high
ENSG00000132591 ERAL1 CHOL 0.014 high
ENSG00000132591 ERAL1 UVM 0.038 high
ENSG00000132591 ERAL1 PAAD 0.0052 low
ENSG00000132591 ERAL1 UCEC 0.0012 low
ENSG00000132591 ERAL1 ACC 0.028 high
ENSG00000132591 ERAL1 LGG 0.0023 low
ENSG00000132591 ERAL1 LUSC 0.017 low
ENSG00000132591 ERAL1 HNSC 0.0081 high
ENSG00000132591 ERAL1 READ 0.0014 low
ENSG00000132591 ERAL1 KICH 0.023 high
ENSG00000132591 ERAL1 LUAD 0.0044 high
ENSG00000132591 ERAL1 PCPG 0.0021 low
ENSG00000132591 ERAL1 UCS 0.011 high
ENSG00000132591 ERAL1 DLBC 0.041 low
ENSG00000132591 ERAL1 KIRC 0.00046 high
ENSG00000132591 ERAL1 BLCA 0.042 high
ENSG00000132591 ERAL1 LAML 0.0067 high
ENSG00000132591 ERAL1 SKCM 0.003 high
ENSG00000132591 ERAL1 LIHC 0.00065 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000132591 ERAL1 COAD Amp 1.747113 0.088123 0.517249 0.237251
ENSG00000132591 ERAL1 THYM Amp 0.609878 0.080570 0.807335 0.081301
ENSG00000132591 ERAL1 SARC Del 2.404369 0.166400 0.428056 0.303502
ENSG00000132591 ERAL1 PCPG Del 5.548083 0.138339 0.666783 0.240741
ENSG00000132591 ERAL1 BLCA Amp 4.156575 0.269520 0.537134 0.431373
ENSG00000132591 ERAL1 BRCA Amp 22.466705 0.368067 0.802497 0.275926
ENSG00000132591 ERAL1 UCEC Amp 5.355643 0.187689 0.676174 0.141002