Ensembl ID ENSG00000132313 Gene ID 51318 Accession 14489
Gene Symbol MRPL35 Alias L35mt;bL35m;MRP-L35 Full Name mitochondrial ribosomal protein L35
Position 2 : 86199355 - 86213790 Length 14436 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p, 10q, and Xp. [provided by RefSeq, Jul 2008]

ENSG00000132313 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000132313 MRPL35 -0.5 4.16e-25 KIRC
ENSG00000132313 MRPL35 -0.7 2.53e-28 COAD
ENSG00000132313 MRPL35 0.85 3.83e-31 LUSC
ENSG00000132313 MRPL35 0.45 9.30e-14 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000132313 MRPL35 Colorectal Cancer 30862482
ENSG00000132313 MRPL35 GBM 31137733
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000132313 MRPL35 SARC 0.0016 low
ENSG00000132313 MRPL35 STAD 0.0036 low
ENSG00000132313 MRPL35 UCEC 0.00048 high
ENSG00000132313 MRPL35 ACC 0.0061 high
ENSG00000132313 MRPL35 LUSC 0.0067 low
ENSG00000132313 MRPL35 READ 0.007 low
ENSG00000132313 MRPL35 KICH 0.039 high
ENSG00000132313 MRPL35 LUAD 0.0088 high
ENSG00000132313 MRPL35 PCPG 0.0022 high
ENSG00000132313 MRPL35 BRCA 0.025 high
ENSG00000132313 MRPL35 COAD 0.039 low
ENSG00000132313 MRPL35 ESCA 0.037 high
ENSG00000132313 MRPL35 OV 0.019 high
ENSG00000132313 MRPL35 DLBC 0.009 low
ENSG00000132313 MRPL35 KIRC 0.0055 low
ENSG00000132313 MRPL35 PRAD 0.038 high
ENSG00000132313 MRPL35 BLCA 0.0075 low
ENSG00000132313 MRPL35 LAML 0.038 high
ENSG00000132313 MRPL35 GBM 0.0038 low
ENSG00000132313 MRPL35 SKCM 0.021 high
ENSG00000132313 MRPL35 CESC 0.009 low
ENSG00000132313 MRPL35 LIHC 0.00012 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency