Ensembl ID ENSG00000132109 Gene ID 6737 Accession 11312
Gene Symbol TRIM21 Alias SSA;RO52;SSA1;RNF81;Ro/SSA Full Name tripartite motif containing 21
Position 11 : 4384897 - 4393702 Length 8806 bases Strand Minus strand
Status Confidence Main interacting RNAsncRNARBP type Canonical_RBPs
Summary This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

ENSG00000132109 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000132109 TRIM21 0.76 8.08e-48 KIRC
ENSG00000132109 TRIM21 -0.8 9.01e-17 LUSC
ENSG00000132109 TRIM21 2.18 2.57e-13 GBM
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000132109 TRIM21 tumor 16630135
ENSG00000132109 TRIM21 tumour 25880119
ENSG00000132109 TRIM21 cancers 26055142
ENSG00000132109 TRIM21 tumors 26398169
ENSG00000132109 TRIM21 tumour 27465491
ENSG00000132109 TRIM21 colon cancer 27830973
ENSG00000132109 TRIM21 brain tumor 29038421
ENSG00000132109 TRIM21 tumors 29925815
ENSG00000132109 TRIM21 tumor 30209217
ENSG00000132109 TRIM21 breast cancer 30288100
ENSG00000132109 TRIM21 colorectal cancer 30367038
ENSG00000132109 TRIM21 breast cancer 30502437
ENSG00000132109 TRIM21 tumors 30573520
ENSG00000132109 TRIM21 bladder cancer 30719818
ENSG00000132109 TRIM21 cancer 30886235
ENSG00000132109 TRIM21 cancer 31540324
ENSG00000132109 TRIM21 breast cancer 31622717
ENSG00000132109 TRIM21 tumour 7492240
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000132109 TRIM21 MESO 0.0024 low
ENSG00000132109 TRIM21 CHOL 0.018 low
ENSG00000132109 TRIM21 UVM 0.018 high
ENSG00000132109 TRIM21 PAAD 0.005 high
ENSG00000132109 TRIM21 UCEC 0.0044 low
ENSG00000132109 TRIM21 ACC 0.049 low
ENSG00000132109 TRIM21 READ 0.013 low
ENSG00000132109 TRIM21 KIRP 0.022 low
ENSG00000132109 TRIM21 KICH 0.034 low
ENSG00000132109 TRIM21 LUAD 0.042 high
ENSG00000132109 TRIM21 OV 0.0093 low
ENSG00000132109 TRIM21 TGCT 0.00081 low
ENSG00000132109 TRIM21 BLCA 0.0044 low
ENSG00000132109 TRIM21 LAML 0.00051 high
ENSG00000132109 TRIM21 GBM 0.04 high
ENSG00000132109 TRIM21 CESC 0.03 low
ENSG00000132109 TRIM21 LIHC 0.00014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000132109 TRIM21 LUSC Del 9.234694 0.145218 0.369015 0.471058
ENSG00000132109 TRIM21 LUAD Del 1.163402 0.057699 0.294821 0.259690
ENSG00000132109 TRIM21 LGG Del 8.961664 0.098768 0.577588 0.198830
ENSG00000132109 TRIM21 SARC Del 1.136188 0.134805 0.510909 0.392996
ENSG00000132109 TRIM21 GBM Del 0.940669 0.055164 0.481020 0.206239
ENSG00000132109 TRIM21 PAAD Del 0.945689 0.050602 0.339183 0.146739
ENSG00000132109 TRIM21 ESCA Del 0.645160 0.094732 0.364402 0.391304
ENSG00000132109 TRIM21 HNSC Del 2.173970 0.070103 0.369167 0.308429
ENSG00000132109 TRIM21 PCPG Del 1.648665 0.078191 0.627234 0.358025
ENSG00000132109 TRIM21 BLCA Del 1.461321 0.090221 0.426730 0.531863
ENSG00000132109 TRIM21 BRCA Del 9.255135 0.111874 0.428005 0.280556
ENSG00000132109 TRIM21 UCEC Del 3.275013 0.074922 0.515309 0.191095
ENSG00000132109 TRIM21 OV Del 30.275132 0.451946 0.603376 0.588946