Ensembl ID ENSG00000131652 Gene ID 79228 Accession 28369
Gene Symbol THOC6 Alias WDR58;fSAP35;MMRFCGU Full Name THO complex subunit 6
Position 16 : 3024035 - 3027755 Length 3721 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary This gene encodes a subunit of the multi-protein THO complex, which is involved in coordination between transcription and mRNA processing. The THO complex is a component of the TREX (transcription/export) complex, which is involved in transcription and export of mRNAs. A missense mutation in this gene is associated with a neurodevelopmental disorder called Beaulieu-Boycott-Innes syndrome. [provided by RefSeq, Dec 2016]

ENSG00000131652 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000131652 THOC6 1.09 8.72e-44 KIRC
ENSG00000131652 THOC6 1.10 1.18e-54 BRCA
ENSG00000131652 THOC6 0.69 5.72e-19 LUSC
ENSG00000131652 THOC6 1.51 7.81e-36 KIRP
ENSG00000131652 THOC6 0.90 1.15e-13 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000131652 THOC6 MESO 0.028 high
ENSG00000131652 THOC6 SARC 0.04 high
ENSG00000131652 THOC6 UVM 0.0083 high
ENSG00000131652 THOC6 UCEC 0.021 low
ENSG00000131652 THOC6 LGG 0.034 high
ENSG00000131652 THOC6 HNSC 0.011 low
ENSG00000131652 THOC6 KICH 0.0071 low
ENSG00000131652 THOC6 PCPG 7e-04 low
ENSG00000131652 THOC6 BRCA 0.022 low
ENSG00000131652 THOC6 UCS 0.024 high
ENSG00000131652 THOC6 ESCA 0.041 low
ENSG00000131652 THOC6 OV 0.016 low
ENSG00000131652 THOC6 LAML 0.014 high
ENSG00000131652 THOC6 CESC 0.0065 low
ENSG00000131652 THOC6 LIHC 0.017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000131652 THOC6 LUSC Del 3.400404 0.098108 0.360484 0.373253
ENSG00000131652 THOC6 BLCA Del 9.265908 0.173542 0.397793 0.421569
ENSG00000131652 THOC6 STAD Del 1.441039 0.071195 0.382053 0.249433
ENSG00000131652 THOC6 OV Del 0.694822 0.173710 0.563211 0.535406