Ensembl ID
ENSG00000131652
Gene ID
79228
Accession
28369
Gene Symbol
THOC6
Alias
WDR58;fSAP35;MMRFCGU
Full Name
THO complex subunit 6
Position
16 : 3024035 - 3027755
Length
3721 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Non-canonical_RBPs
Summary
This gene encodes a subunit of the multi-protein THO complex, which is involved in coordination between transcription and mRNA processing. The THO complex is a component of the TREX (transcription/export) complex, which is involved in transcription and export of mRNAs. A missense mutation in this gene is associated with a neurodevelopmental disorder called Beaulieu-Boycott-Innes syndrome. [provided by RefSeq, Dec 2016]
ENSG00000131652 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000131652
THOC6
1.09
8.72e-44
KIRC
ENSG00000131652
THOC6
1.10
1.18e-54
BRCA
ENSG00000131652
THOC6
0.69
5.72e-19
LUSC
ENSG00000131652
THOC6
1.51
7.81e-36
KIRP
ENSG00000131652
THOC6
0.90
1.15e-13
UCEC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000131652
THOC6
MESO
0.028
high
show
ENSG00000131652
THOC6
SARC
0.04
high
show
ENSG00000131652
THOC6
UVM
0.0083
high
show
ENSG00000131652
THOC6
UCEC
0.021
low
show
ENSG00000131652
THOC6
LGG
0.034
high
show
ENSG00000131652
THOC6
HNSC
0.011
low
show
ENSG00000131652
THOC6
KICH
0.0071
low
show
ENSG00000131652
THOC6
PCPG
7e-04
low
show
ENSG00000131652
THOC6
BRCA
0.022
low
show
ENSG00000131652
THOC6
UCS
0.024
high
show
ENSG00000131652
THOC6
ESCA
0.041
low
show
ENSG00000131652
THOC6
OV
0.016
low
show
ENSG00000131652
THOC6
LAML
0.014
high
show
ENSG00000131652
THOC6
CESC
0.0065
low
show
ENSG00000131652
THOC6
LIHC
0.017
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000131652
THOC6
LUSC
Del
3.400404
0.098108
0.360484
0.373253
ENSG00000131652
THOC6
BLCA
Del
9.265908
0.173542
0.397793
0.421569
ENSG00000131652
THOC6
STAD
Del
1.441039
0.071195
0.382053
0.249433
ENSG00000131652
THOC6
OV
Del
0.694822
0.173710
0.563211
0.535406
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.