Ensembl ID ENSG00000131504 Gene ID 1729 Accession 2876
Gene Symbol DIAPH1 Alias DIA1;DRF1;DFNA1;LFHL1;SCBMS;hDIA1;mDia1 Full Name diaphanous related formin 1
Position 5 : 141515021 - 141619055 Length 104035 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000131504 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000131504 0.82 2.76e-14 KICH
ENSG00000131504 -0.7 9.77e-23 LUSC
ENSG00000131504 0.64 1.58e-13 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000131504 tumor 19768111
ENSG00000131504 tumor 22206044
ENSG00000131504 tumor 22693380
ENSG00000131504 colorectal cancer 24105619
ENSG00000131504 breast cancer 24317603
ENSG00000131504 tumour 24694742
ENSG00000131504 colon cancer 25413277
ENSG00000131504 tumor 26124177
ENSG00000131504 cancers 26893363
ENSG00000131504 tumor 27911711
ENSG00000131504 HNSCC 28827448
ENSG00000131504 tumors 29035824
ENSG00000131504 ovarian cancer 30094535
ENSG00000131504 tumor 30733838
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000131504 STAD 0.018 low
ENSG00000131504 PAAD 0.00052 high
ENSG00000131504 UCEC 0.03 high
ENSG00000131504 ACC 0.029 high
ENSG00000131504 LUSC 0.014 high
ENSG00000131504 READ 0.0059 low
ENSG00000131504 KIRP 0.05 low
ENSG00000131504 THYM 0.015 low
ENSG00000131504 COAD 0.0052 low
ENSG00000131504 UCS 0.016 high
ENSG00000131504 OV 0.0048 high
ENSG00000131504 PRAD 0.0086 high
ENSG00000131504 TGCT 0.015 high
ENSG00000131504 LAML 0.038 low
ENSG00000131504 GBM 0.033 high
ENSG00000131504 SKCM 0.031 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000131504 LAML Del 6.887040 0.097495 0.800690 0.089005
ENSG00000131504 LGG Del 1.881657 0.051283 0.395828 0.093567
ENSG00000131504 SKCM Del 7.404516 0.146910 0.492329 0.354223
ENSG00000131504 KIRC Amp 51.113742 0.292379 0.544490 0.607955