Ensembl ID ENSG00000131503 Gene ID 54882 Accession 24714
Gene Symbol ANKHD1 Alias MASK;MASK1;VBARP;PP2500 Full Name ankyrin repeat and KH domain containing 1
Position 5 : 140401814 - 140539856 Length 138043 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Sep 2010]

ENSG00000131503 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000131503 ANKHD1 1.00 1.50e-37 KIRC
ENSG00000131503 ANKHD1 0.83 2.21e-11 KICH
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000131503 ANKHD1 cancers 23142581
ENSG00000131503 ANKHD1 prostate cancer 24726915
ENSG00000131503 ANKHD1 cancer 25424858
ENSG00000131503 ANKHD1 pancreatic cancer 25425966
ENSG00000131503 ANKHD1 tumour 25483783
ENSG00000131503 ANKHD1 tumor 25523139
ENSG00000131503 ANKHD1 tumor 27670291
ENSG00000131503 ANKHD1 renal cancer 29695508
ENSG00000131503 ANKHD1 tumor 30555746
ENSG00000131503 ANKHD1 tumor 30646949
ENSG00000131503 ANKHD1 tumour 31443305
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000131503 ANKHD1 THCA 0.04 high
ENSG00000131503 ANKHD1 ACC 0.011 high
ENSG00000131503 ANKHD1 READ 0.011 low
ENSG00000131503 ANKHD1 KICH 0.0026 high
ENSG00000131503 ANKHD1 LUAD 0.014 low
ENSG00000131503 ANKHD1 PCPG 0.00089 low
ENSG00000131503 ANKHD1 KIRC 0.043 low
ENSG00000131503 ANKHD1 PRAD 0.05 high
ENSG00000131503 ANKHD1 BLCA 6e-04 low
ENSG00000131503 ANKHD1 GBM 0.019 low
ENSG00000131503 ANKHD1 LIHC 0.05 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000131503 ANKHD1 LAML Del 6.887040 0.098062 0.800690 0.089005
ENSG00000131503 ANKHD1 LGG Del 1.403584 0.046640 0.399767 0.089669
ENSG00000131503 ANKHD1 ACC Amp 1.656823 0.409187 1.300433 0.677778
ENSG00000131503 ANKHD1 SKCM Del 5.867539 0.131275 0.499850 0.343324
ENSG00000131503 ANKHD1 KIRC Amp 51.061677 0.292110 0.543534 0.609848