Ensembl ID ENSG00000131469 Gene ID 6155 Accession 10328
Gene Symbol RPL27 Alias L27;eL27;DBA16 Full Name ribosomal protein L27
Position 17 : 42998273 - 43002959 Length 4687 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L27e family of ribosomal proteins and a component of the 60S subunit. A splice site mutation in this gene has been identified in a Diamond-Blackfan anemia (DBA) patient. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Mar 2017]

ENSG00000131469 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000131469 RPL27 0.62 7.90e-15 KIRC
ENSG00000131469 RPL27 0.97 3.72e-16 KIRP
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000131469 RPL27 tumor 19650912
ENSG00000131469 RPL27 tumor 24885929
ENSG00000131469 RPL27 head and neck tumor 30128175
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000131469 RPL27 UVM 0.026 low
ENSG00000131469 RPL27 PAAD 0.038 high
ENSG00000131469 RPL27 UCEC 0.027 low
ENSG00000131469 RPL27 ACC 0.00032 high
ENSG00000131469 RPL27 LGG 5e-04 low
ENSG00000131469 RPL27 LUSC 0.028 low
ENSG00000131469 RPL27 HNSC 0.042 high
ENSG00000131469 RPL27 READ 0.0041 low
ENSG00000131469 RPL27 PCPG 0.0043 high
ENSG00000131469 RPL27 BRCA 0.0017 low
ENSG00000131469 RPL27 COAD 0.034 low
ENSG00000131469 RPL27 KIRC 0.00027 high
ENSG00000131469 RPL27 LAML 0.022 low
ENSG00000131469 RPL27 GBM 0.032 low
ENSG00000131469 RPL27 LIHC 0.0026 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000131469 RPL27 ACC Del 1.947196 0.144353 0.571631 0.277778
ENSG00000131469 RPL27 PCPG Del 2.929986 0.100914 0.641569 0.185185
ENSG00000131469 RPL27 BRCA Del 7.152637 0.102952 0.429583 0.341667
ENSG00000131469 RPL27 PRAD Del 1.291248 0.079878 0.424200 0.115854
ENSG00000131469 RPL27 UCEC Del 5.207437 0.089986 0.581538 0.211503