Ensembl ID ENSG00000131018 Gene ID 23345 Accession 17089
Gene Symbol SYNE1 Alias 8B;AMC3;AMCM;CPG2;ARCA1;EDMD4;KASH1;MYNE1;Nesp1;SCAR8;C6orf98;dJ45H2.2 Full Name spectrin repeat containing nuclear envelope protein 1
Position 6 : 152121687 - 152637801 Length 516115 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

ENSG00000131018 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000131018 -1.0 4.55e-31 KIRC
ENSG00000131018 -2.5 3.85e-21 BLCA
ENSG00000131018 -1.4 1.76e-59 BRCA
ENSG00000131018 -1.3 6.88e-11 COAD
ENSG00000131018 -2.1 7.17e-15 KICH
ENSG00000131018 -3.1 9.12e-84 LUSC
ENSG00000131018 -1.1 4.20e-12 KIRP
ENSG00000131018 -1.3 3.56e-25 LIHC
ENSG00000131018 -2.7 1.70e-32 UCEC
ENSG00000131018 -1.1 2.02e-15 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000131018 tumors 18339850
ENSG00000131018 Tumor 18507500
ENSG00000131018 Ovarian Cancer 20056644
ENSG00000131018 GBM 21555372
ENSG00000131018 cancers 22768332
ENSG00000131018 cancers 23830188
ENSG00000131018 colorectal cancer 24280874
ENSG00000131018 cancer 24781983
ENSG00000131018 cancer 25010424
ENSG00000131018 colorectal cancer 25538088
ENSG00000131018 tumor 25786087
ENSG00000131018 cancer 26352260
ENSG00000131018 GBM 27160712
ENSG00000131018 tumors 27782820
ENSG00000131018 HNSCC 28324520
ENSG00000131018 tumours 28387377
ENSG00000131018 cancer 28427185
ENSG00000131018 oral cancer 29315816
ENSG00000131018 tumors 29340043
ENSG00000131018 cervical cancer 29623014
ENSG00000131018 colorectal cancers 29871594
ENSG00000131018 colorectal cancer 29937994
ENSG00000131018 gastric cancer 30078278
ENSG00000131018 benign tumors 30194396
ENSG00000131018 cancers 30740464
ENSG00000131018 cancer 30809433
ENSG00000131018 cancer 30828495
ENSG00000131018 lung cancer 30956756
ENSG00000131018 breast cancer 30988301
ENSG00000131018 cancer 31501460
ENSG00000131018 liver cancer 31741263
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000131018 SARC 0.0021 low
ENSG00000131018 UVM 0.036 low
ENSG00000131018 PAAD 0.011 low
ENSG00000131018 THCA 0.0013 high
ENSG00000131018 ACC 0.016 high
ENSG00000131018 LUSC 0.0089 high
ENSG00000131018 HNSC 0.0089 low
ENSG00000131018 READ 0.012 high
ENSG00000131018 LUAD 0.0014 low
ENSG00000131018 PCPG 0.023 high
ENSG00000131018 UCS 0.035 low
ENSG00000131018 BLCA 0.015 low
ENSG00000131018 GBM 0.007 low
ENSG00000131018 SKCM 0.00052 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000131018 LUAD Del 1.228881 0.058539 0.374046 0.500000
ENSG00000131018 LGG Del 0.974833 0.041998 0.568187 0.152047
ENSG00000131018 CESC Del 1.700870 0.086245 0.472720 0.318644
ENSG00000131018 SARC Amp 1.589996 0.309789 0.785322 0.260700
ENSG00000131018 GBM Del 3.673823 0.082184 0.550578 0.266898
ENSG00000131018 SKCM Del 5.455481 0.126850 0.558095 0.602180
ENSG00000131018 LIHC Del 4.723607 0.118506 0.608139 0.375676
ENSG00000131018 BLCA Del 0.648777 0.075361 0.369469 0.453431
ENSG00000131018 BRCA Del 2.988278 0.081299 0.460672 0.313889
ENSG00000131018 UCEC Del 1.265651 0.055438 0.425240 0.064935
ENSG00000131018 MESO Del 1.729258 0.165509 0.540760 0.448276
ENSG00000131018 KIRC Del 7.235384 0.055978 0.459647 0.287879
ENSG00000131018 UVM Del 2.265284 0.115032 0.854151 0.300000
ENSG00000131018 OV Del 23.623631 0.407630 0.645183 0.618307