Ensembl ID ENSG00000130813 Gene ID 55337 Accession 25649
Gene Symbol SHFL Alias SFL;IRAV;RyDEN;C19orf66 Full Name shiftless antiviral inhibitor of ribosomal frameshifting
Position 19 : 10086317 - 10093243 Length 6927 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene is an interferon stimulated gene (ISG) that inhibits viral replication. The encoded protein binds nucleic acids and inhibits programmed -1 ribosomal frameshifting required for translation by many RNA viruses. Viruses inhibited by the protein include Zika virus, dengue virus and the coronaviruses, SARS-CoV and SARS-CoV2. [provided by RefSeq, Aug 2021]

ENSG00000130813 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000130813 0.65 3.60e-19 KIRC
ENSG00000130813 0.94 7.49e-16 HNSC
ENSG00000130813 -1.9 1.88e-16 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000130813 tumor 10393807
ENSG00000130813 tumor 24362332
ENSG00000130813 Tumor 29416939
ENSG00000130813 bone cancer 29867362
ENSG00000130813 lung cancer 30891063
ENSG00000130813 tumor 7657525
ENSG00000130813 tumor 7929634
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000130813 MESO 0.0028 low
ENSG00000130813 SARC 0.00055 low
ENSG00000130813 STAD 0.017 low
ENSG00000130813 CHOL 0.0035 low
ENSG00000130813 UVM 0.00014 high
ENSG00000130813 THCA 0.0042 low
ENSG00000130813 ACC 0.0048 high
ENSG00000130813 LUSC 0.014 high
ENSG00000130813 HNSC 0.018 low
ENSG00000130813 THYM 0.041 high
ENSG00000130813 BRCA 0.00074 low
ENSG00000130813 COAD 0.0036 high
ENSG00000130813 ESCA 0.023 high
ENSG00000130813 OV 0.0083 low
ENSG00000130813 DLBC 0.002 high
ENSG00000130813 PRAD 0.012 high
ENSG00000130813 LAML 2e-04 high
ENSG00000130813 GBM 0.0022 high
ENSG00000130813 SKCM 0.0058 low
ENSG00000130813 CESC 0.0091 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000130813 UCS Amp 1.084949 0.557729 0.995501 0.321429
ENSG00000130813 UCS Del 0.800599 0.208797 0.565205 0.410714
ENSG00000130813 SARC Amp 1.203894 0.289523 0.668034 0.424125
ENSG00000130813 LIHC Del 4.640610 0.117628 0.465902 0.221622
ENSG00000130813 UCEC Amp 4.509545 0.175065 0.797001 0.137291
ENSG00000130813 UCEC Del 5.715651 0.093602 0.518270 0.142857
ENSG00000130813 OV Amp 10.735492 0.559405 0.915872 0.392055
ENSG00000130813 OV Del 1.568476 0.194279 0.535342 0.338515