Ensembl ID ENSG00000130811 Gene ID 8666 Accession 3274
Gene Symbol EIF3G Alias EIF3S4;EIF3-P42;eIF3-p44;eIF3-delta Full Name eukaryotic translation initiation factor 3 subunit G
Position 19 : 10115014 - 10119918 Length 4905 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex, which is required for initiation of protein translation. An N-terminal caspase cleavage product of the encoded protein may stimulate degradation of DNA. A mutation in this gene is associated with narcolepsy. [provided by RefSeq, Jul 2016]

ENSG00000130811 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000130811 EIF3G breast cancer 26935993
ENSG00000130811 EIF3G cancer 30214237
ENSG00000130811 EIF3G colorectal cancer 30899366
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000130811 EIF3G MESO 0.01 low
ENSG00000130811 EIF3G SARC 0.0028 low
ENSG00000130811 EIF3G STAD 0.016 low
ENSG00000130811 EIF3G UVM 0.0039 low
ENSG00000130811 EIF3G PAAD 0.035 low
ENSG00000130811 EIF3G UCEC 0.023 low
ENSG00000130811 EIF3G ACC 0.00055 high
ENSG00000130811 EIF3G HNSC 0.024 low
ENSG00000130811 EIF3G KIRP 0.033 low
ENSG00000130811 EIF3G PCPG 0.032 low
ENSG00000130811 EIF3G BRCA 0.0092 low
ENSG00000130811 EIF3G ESCA 0.0089 low
ENSG00000130811 EIF3G OV 0.00038 low
ENSG00000130811 EIF3G KIRC 0.0024 high
ENSG00000130811 EIF3G LAML 0.00016 high
ENSG00000130811 EIF3G GBM 0.042 low
ENSG00000130811 EIF3G SKCM 0.025 high
ENSG00000130811 EIF3G CESC 0.017 low
ENSG00000130811 EIF3G LIHC 0.05 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000130811 EIF3G UCS Amp 1.084949 0.557729 0.995501 0.321429
ENSG00000130811 EIF3G UCS Del 0.800599 0.208797 0.565205 0.410714
ENSG00000130811 EIF3G SARC Amp 1.203894 0.289523 0.668034 0.424125
ENSG00000130811 EIF3G LIHC Del 4.640610 0.117628 0.465902 0.221622
ENSG00000130811 EIF3G UCEC Amp 5.179884 0.185034 0.811912 0.139147
ENSG00000130811 EIF3G UCEC Del 4.398929 0.084161 0.501533 0.139147
ENSG00000130811 EIF3G OV Amp 11.999979 0.580060 0.926518 0.395509
ENSG00000130811 EIF3G OV Del 1.568476 0.194279 0.535342 0.338515