Ensembl ID ENSG00000130707 Gene ID 445 Accession 758
Gene Symbol ASS1 Alias ASS;CTLN1 Full Name argininosuccinate synthase 1
Position 9 : 130444961 - 130501274 Length 56314 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2012]

ENSG00000130707 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000130707 -2.7 5.98e-83 KIRC
ENSG00000130707 -5.0 3.03e-41 KICH
ENSG00000130707 -1.2 6.01e-17 PRAD
ENSG00000130707 -3.1 3.25e-36 KIRP
ENSG00000130707 -1.7 8.76e-19 LIHC
ENSG00000130707 -4.0 2.76e-21 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000130707 tumour 19374748
ENSG00000130707 ovarian cancer 19533750
ENSG00000130707 tumours 20104527
ENSG00000130707 tumour 20808309
ENSG00000130707 cancers 21152246
ENSG00000130707 tumor 21901069
ENSG00000130707 tumours 22134507
ENSG00000130707 tumour 22426640
ENSG00000130707 tumour 22472884
ENSG00000130707 prostate cancer 22546217
ENSG00000130707 Tumours 22764101
ENSG00000130707 tumor 23293541
ENSG00000130707 tumour 23328665
ENSG00000130707 tumor 23549872
ENSG00000130707 cancers 23643539
ENSG00000130707 prostate tumor 23665532
ENSG00000130707 tumor 23897555
ENSG00000130707 tumors 23979920
ENSG00000130707 cancer 24040099
ENSG00000130707 tumor 24113174
ENSG00000130707 bladder cancer 24285724
ENSG00000130707 cancer 24286268
ENSG00000130707 tumor 24416132
ENSG00000130707 tumor 24453997
ENSG00000130707 breast cancer 24692592
ENSG00000130707 tumours 24987688
ENSG00000130707 prostate cancer 25122679
ENSG00000130707 tumors 25164070
ENSG00000130707 pancreatic cancer 25240403
ENSG00000130707 tumors 25304236
ENSG00000130707 tumors 25322968
ENSG00000130707 gastric cancer 25333458
ENSG00000130707 tumors 25362567
ENSG00000130707 GBM 25567351
ENSG00000130707 tumor 25616743
ENSG00000130707 prostate cancer 25650867
ENSG00000130707 AML 25710880
ENSG00000130707 tumor 25749046
ENSG00000130707 cancer 25775142
ENSG00000130707 tumour 25872475
ENSG00000130707 AMLs 25896651
ENSG00000130707 tumor 25928182
ENSG00000130707 tumor 26425646
ENSG00000130707 cancers 26560030
ENSG00000130707 tumor 26642391
ENSG00000130707 AML 26674644
ENSG00000130707 tumors 26771234
ENSG00000130707 cancer 26839743
ENSG00000130707 breast cancers 26902604
ENSG00000130707 tumours 26972697
ENSG00000130707 tumor 26978353
ENSG00000130707 tumors 26982031
ENSG00000130707 liver cancer 27296761
ENSG00000130707 cancer 27308634
ENSG00000130707 cancers 27452468
ENSG00000130707 ovarian cancers 27499892
ENSG00000130707 cancers 27584578
ENSG00000130707 cancers 27683125
ENSG00000130707 cancers 27689335
ENSG00000130707 tumors 27735949
ENSG00000130707 small cell lung cancer 27765932
ENSG00000130707 tumors 27913198
ENSG00000130707 bladder cancer 27979310
ENSG00000130707 Cancers 28122247
ENSG00000130707 pancreatic cancer 28187218
ENSG00000130707 Colorectal Cancer 28229591
ENSG00000130707 GBM 28245795
ENSG00000130707 tumors 28358054
ENSG00000130707 cancer 28358368
ENSG00000130707 tumors 28388291
ENSG00000130707 cancers 28464918
ENSG00000130707 tumor 28560349
ENSG00000130707 tumors 28587170
ENSG00000130707 cancers 28616574
ENSG00000130707 cancer 28633644
ENSG00000130707 cancer 28750681
ENSG00000130707 pancreatic cancer 28832976
ENSG00000130707 tumors 28883660
ENSG00000130707 cancers 28900115
ENSG00000130707 cancer 28938609
ENSG00000130707 tumours 28969007
ENSG00000130707 cancer 29168171
ENSG00000130707 cancer 29401583
ENSG00000130707 GBM 29422017
ENSG00000130707 cancer 29453600
ENSG00000130707 tumors 29524617
ENSG00000130707 tumors 29597093
ENSG00000130707 cancers 29721066
ENSG00000130707 endometrial cancer 29731978
ENSG00000130707 tumour 29776373
ENSG00000130707 tumor 30008833
ENSG00000130707 cancer 30082427
ENSG00000130707 cancers 30108309
ENSG00000130707 tumors 30155941
ENSG00000130707 tumor 30214636
ENSG00000130707 tumour 30334010
ENSG00000130707 breast cancer 30393775
ENSG00000130707 tumors 30429453
ENSG00000130707 tumor 30429607
ENSG00000130707 tumour 30546006
ENSG00000130707 Cancer 30573518
ENSG00000130707 tumors 30605863
ENSG00000130707 tumors 30613774
ENSG00000130707 cancers 30651925
ENSG00000130707 tumors 30808864
ENSG00000130707 AML 30813354
ENSG00000130707 cancer 30883650
ENSG00000130707 ovarian cancer 30887252
ENSG00000130707 breast cancers 30918839
ENSG00000130707 tumors 31000693
ENSG00000130707 tumor 31047837
ENSG00000130707 tumours 31052256
ENSG00000130707 cancer 31108873
ENSG00000130707 Tumors 31113844
ENSG00000130707 AML 31192118
ENSG00000130707 tumors 31231467
ENSG00000130707 AML 31319822
ENSG00000130707 tumors 31354721
ENSG00000130707 pancreatic cancers 31395686
ENSG00000130707 tumor 31824848
ENSG00000130707 tumors 31887630
ENSG00000130707 tumors 31903153
ENSG00000130707 small cell lung cancer 31954097
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000130707 MESO 0.0021 low
ENSG00000130707 SARC 0.022 high
ENSG00000130707 STAD 0.012 low
ENSG00000130707 PAAD 0.02 high
ENSG00000130707 ACC 0.0065 high
ENSG00000130707 LGG 0.0086 high
ENSG00000130707 HNSC 0.00011 high
ENSG00000130707 LUAD 0.014 low
ENSG00000130707 THYM 0.0059 high
ENSG00000130707 BRCA 0.038 high
ENSG00000130707 DLBC 0.025 low
ENSG00000130707 BLCA 0.0034 low
ENSG00000130707 LAML 0.0014 low
ENSG00000130707 CESC 0.007 low
ENSG00000130707 LIHC 0.036 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000130707 UCEC Del 0.946417 0.051019 0.535935 0.244898
ENSG00000130707 OV Del 3.856149 0.231863 0.566400 0.588946