Ensembl ID ENSG00000130589 Gene ID 85441 Accession 30021
Gene Symbol HELZ2 Alias PDIP-1;PRIC285 Full Name helicase with zinc finger 2
Position 20 : 63558086 - 63574239 Length 16154 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is a nuclear transcriptional co-activator for peroxisome proliferator activated receptor alpha. The encoded protein contains a zinc finger and is a helicase that appears to be part of the peroxisome proliferator activated receptor alpha interacting complex. This gene is a member of the DNA2/NAM7 helicase gene family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000130589 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000130589 HELZ2 0.86 2.41e-33 KIRC
ENSG00000130589 HELZ2 1.18 2.58e-15 HNSC
ENSG00000130589 HELZ2 1.16 2.72e-36 BRCA
ENSG00000130589 HELZ2 0.98 2.02e-13 COAD
ENSG00000130589 HELZ2 1.80 4.81e-12 READ
ENSG00000130589 HELZ2 0.72 4.57e-12 PRAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000130589 HELZ2 tumor 23551967
ENSG00000130589 HELZ2 Endometrial Cancer 31787999
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000130589 HELZ2 MESO 0.025 high
ENSG00000130589 HELZ2 SARC 0.038 low
ENSG00000130589 HELZ2 STAD 0.023 low
ENSG00000130589 HELZ2 CHOL 0.035 low
ENSG00000130589 HELZ2 UVM 0.035 high
ENSG00000130589 HELZ2 PAAD 0.022 high
ENSG00000130589 HELZ2 UCEC 0.0012 high
ENSG00000130589 HELZ2 ACC 0.0013 high
ENSG00000130589 HELZ2 LUSC 0.012 high
ENSG00000130589 HELZ2 HNSC 0.027 low
ENSG00000130589 HELZ2 LUAD 0.037 high
ENSG00000130589 HELZ2 PCPG 0.024 low
ENSG00000130589 HELZ2 THYM 0.0049 low
ENSG00000130589 HELZ2 UCS 0.039 high
ENSG00000130589 HELZ2 DLBC 0.0015 high
ENSG00000130589 HELZ2 PRAD 0.034 high
ENSG00000130589 HELZ2 TGCT 0.0021 high
ENSG00000130589 HELZ2 LAML 0.00025 high
ENSG00000130589 HELZ2 SKCM 0.029 low
ENSG00000130589 HELZ2 CESC 0.043 low
ENSG00000130589 HELZ2 LIHC 0.013 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000130589 HELZ2 LUAD Amp 14.033709 0.326989 0.562509 0.484496
ENSG00000130589 HELZ2 READ Amp 1.468889 0.165203 1.287549 0.884848
ENSG00000130589 HELZ2 SKCM Amp 1.236415 0.138111 0.644584 0.514986
ENSG00000130589 HELZ2 LIHC Amp 0.955468 0.119410 0.581915 0.340541
ENSG00000130589 HELZ2 STAD Amp 1.509494 0.156328 0.678181 0.643991
ENSG00000130589 HELZ2 PRAD Amp 0.767240 0.046659 0.393229 0.083333
ENSG00000130589 HELZ2 UCEC Amp 3.457937 0.158517 0.678097 0.276438
ENSG00000130589 HELZ2 OV Amp 9.246972 0.533755 0.881944 0.692573