Ensembl ID ENSG00000130520 Gene ID 25804 Accession 17259
Gene Symbol LSM4 Alias GRP;YER112W Full Name LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
Position 19 : 18306236 - 18323112 Length 16877 bases Strand Minus strand
Status Confidence Main interacting RNAssnRNARBP type Canonical_RBPs
Summary This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

ENSG00000130520 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000130520 LSM4 0.90 2.36e-11 BLCA
ENSG00000130520 LSM4 1.39 2.93e-87 BRCA
ENSG00000130520 LSM4 1.25 1.16e-41 LUSC
ENSG00000130520 LSM4 0.97 1.58e-18 LIHC
ENSG00000130520 LSM4 1.50 1.10e-35 UCEC
ENSG00000130520 LSM4 0.60 2.69e-11 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000130520 LSM4 tumor 23199131
ENSG00000130520 LSM4 cancer 27366143
ENSG00000130520 LSM4 colorectal cancer 29415677
ENSG00000130520 LSM4 cancer 29463416
ENSG00000130520 LSM4 liver cancer 29866044
ENSG00000130520 LSM4 tumor 30519576
ENSG00000130520 LSM4 cancer 31270132
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000130520 LSM4 MESO 0.047 low
ENSG00000130520 LSM4 STAD 0.018 low
ENSG00000130520 LSM4 PAAD 0.0071 high
ENSG00000130520 LSM4 UCEC 0.0067 high
ENSG00000130520 LSM4 THCA 0.023 low
ENSG00000130520 LSM4 HNSC 0.044 low
ENSG00000130520 LSM4 KIRP 0.037 low
ENSG00000130520 LSM4 LUAD 0.0032 high
ENSG00000130520 LSM4 PCPG 0.036 low
ENSG00000130520 LSM4 THYM 0.0056 low
ENSG00000130520 LSM4 UCS 0.018 high
ENSG00000130520 LSM4 KIRC 0.00023 high
ENSG00000130520 LSM4 LAML 0.00021 high
ENSG00000130520 LSM4 SKCM 0.011 high
ENSG00000130520 LSM4 LIHC 0.00097 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000130520 LSM4 UCEC Amp 6.870261 0.208086 0.788842 0.170686
ENSG00000130520 LSM4 OV Amp 11.742137 0.575993 0.813190 0.495682