Ensembl ID
ENSG00000130299
Gene ID
84705
Accession
14880
Gene Symbol
GTPBP3
Alias
MSS1;MTGP1;THDF1;GTPBG3;COXPD23
Full Name
GTP binding protein 3, mitochondrial
Position
19 : 17334920 - 17342731
Length
7812 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs tRNA RBP type
Canonical_RBPs
Summary
This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2010]
ENSG00000130299 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000130299
GTPBP3
0.67
3.88e-27
KIRC
ENSG00000130299
GTPBP3
1.07
6.28e-18
BLCA
ENSG00000130299
GTPBP3
0.91
5.65e-48
BRCA
ENSG00000130299
GTPBP3
1.00
6.60e-29
COAD
ENSG00000130299
GTPBP3
0.78
1.40e-13
KICH
ENSG00000130299
GTPBP3
1.36
5.16e-13
READ
ENSG00000130299
GTPBP3
1.43
9.37e-46
LUSC
ENSG00000130299
GTPBP3
0.53
1.16e-18
PRAD
ENSG00000130299
GTPBP3
0.72
1.25e-24
KIRP
ENSG00000130299
GTPBP3
0.59
2.89e-15
LIHC
ENSG00000130299
GTPBP3
0.83
1.19e-23
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000130299
GTPBP3
MESO
0.0022
high
show
ENSG00000130299
GTPBP3
SARC
0.026
high
show
ENSG00000130299
GTPBP3
STAD
0.0067
low
show
ENSG00000130299
GTPBP3
PAAD
0.027
low
show
ENSG00000130299
GTPBP3
UCEC
0.0046
high
show
ENSG00000130299
GTPBP3
ACC
0.0029
high
show
ENSG00000130299
GTPBP3
LGG
0.013
high
show
ENSG00000130299
GTPBP3
HNSC
0.027
low
show
ENSG00000130299
GTPBP3
PCPG
0.011
low
show
ENSG00000130299
GTPBP3
COAD
0.0088
high
show
ENSG00000130299
GTPBP3
DLBC
0.0029
low
show
ENSG00000130299
GTPBP3
PRAD
0.0042
high
show
ENSG00000130299
GTPBP3
LAML
0.018
high
show
ENSG00000130299
GTPBP3
CESC
0.017
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000130299
GTPBP3
UCEC
Amp
7.992180
0.222382
0.817742
0.170686
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