Ensembl ID
ENSG00000129245
Gene ID
9513
Accession
4024
Gene Symbol
FXR2
Alias
FXR2P;FMR1L2
Full Name
FMR1 autosomal homolog 2
Position
17 : 7591230 - 7614897
Length
23668 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitive disability syndrome. [provided by RefSeq, Jul 2008]
ENSG00000129245 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000129245
FXR2
-0.3
3.10e-18
KIRC
ENSG00000129245
FXR2
-1.2
7.63e-12
GBM
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000129245
FXR2
lung cancer
25205123
ENSG00000129245
FXR2
HNSCC
27606879
ENSG00000129245
FXR2
tumors
28767039
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000129245
FXR2
SARC
0.0034
high
show
ENSG00000129245
FXR2
STAD
0.033
low
show
ENSG00000129245
FXR2
CHOL
0.013
high
show
ENSG00000129245
FXR2
UVM
0.049
low
show
ENSG00000129245
FXR2
HNSC
0.0052
high
show
ENSG00000129245
FXR2
KIRP
0.034
low
show
ENSG00000129245
FXR2
LUAD
0.0042
high
show
ENSG00000129245
FXR2
PCPG
6e-04
low
show
ENSG00000129245
FXR2
THYM
0.01
low
show
ENSG00000129245
FXR2
COAD
0.0042
high
show
ENSG00000129245
FXR2
KIRC
0.026
low
show
ENSG00000129245
FXR2
LIHC
0.042
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000129245
FXR2
SARC
Del
36.242398
0.574184
0.657884
0.486381
ENSG00000129245
FXR2
GBM
Del
6.536323
0.103574
0.519300
0.168111
ENSG00000129245
FXR2
PAAD
Del
0.661177
0.044130
0.389425
0.489130
ENSG00000129245
FXR2
LIHC
Del
9.410201
0.161227
0.662386
0.608108
ENSG00000129245
FXR2
PCPG
Del
0.992968
0.064825
0.647723
0.401235
ENSG00000129245
FXR2
DLBC
Del
0.740752
0.126309
0.522682
0.229167
ENSG00000129245
FXR2
BRCA
Del
3.247276
0.082903
0.490250
0.609259
ENSG00000129245
FXR2
PRAD
Del
32.345655
0.260100
0.562065
0.325203
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