Ensembl ID ENSG00000128908 Gene ID 54617 Accession 26956
Gene Symbol INO80 Alias INOC1;INO80A Full Name INO80 complex ATPase subunit
Position 15 : 40978880 - 41116280 Length 137401 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene encodes a subunit of the chromatin remodeling complex, which is classified into subfamilies depending on sequence features apart from the conserved ATPase domain. This protein is the catalytic ATPase subunit of the INO80 chromatin remodeling complex, which is characterized by a DNA-binding domain. This protein is proposed to bind DNA and be recruited by the YY1 transcription factor to activate certain genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

ENSG00000128908 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000128908 -0.5 1.34e-17 LUSC
ENSG00000128908 -0.4 2.27e-17 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000128908 tumor 20302916
ENSG00000128908 cancer 22210892
ENSG00000128908 cancer 23979016
ENSG00000128908 tumour 25283999
ENSG00000128908 tumor 27340176
ENSG00000128908 cancer 27535137
ENSG00000128908 non-small cell lung cancer 27641337
ENSG00000128908 thyroid cancer 27779717
ENSG00000128908 Cancer 28122867
ENSG00000128908 colon cancer 29383140
ENSG00000128908 cancers 29462149
ENSG00000128908 anaplastic thyroid cancer 29561707
ENSG00000128908 tumor 31657441
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000128908 MESO 0.00048 low
ENSG00000128908 SARC 0.0063 low
ENSG00000128908 UVM 0.002 high
ENSG00000128908 PAAD 0.044 high
ENSG00000128908 ACC 0.0046 high
ENSG00000128908 LUSC 0.017 high
ENSG00000128908 HNSC 0.0089 low
ENSG00000128908 READ 0.035 low
ENSG00000128908 KICH 0.019 high
ENSG00000128908 BRCA 0.0076 high
ENSG00000128908 ESCA 0.034 low
ENSG00000128908 OV 0.033 high
ENSG00000128908 PRAD 0.034 high
ENSG00000128908 BLCA 0.0083 high
ENSG00000128908 SKCM 0.00069 low
ENSG00000128908 LIHC 0.012 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000128908 LUSC Del 2.309252 0.086655 0.335378 0.353293
ENSG00000128908 LUAD Del 6.843786 0.105957 0.328816 0.529070
ENSG00000128908 CESC Del 2.828619 0.103494 0.460361 0.240678
ENSG00000128908 COAD Del 4.885410 0.079938 0.477215 0.383592
ENSG00000128908 UCS Del 4.537842 0.448526 0.536622 0.750000
ENSG00000128908 GBM Del 7.809238 0.111830 0.516152 0.249567
ENSG00000128908 SKCM Del 9.524085 0.164610 0.523496 0.250681
ENSG00000128908 DLBC Del 1.428712 0.166909 0.558667 0.229167
ENSG00000128908 BRCA Del 10.021744 0.114881 0.408987 0.363889
ENSG00000128908 STAD Del 2.359628 0.082979 0.340288 0.272109
ENSG00000128908 UCEC Del 5.670979 0.093200 0.520163 0.263451
ENSG00000128908 MESO Del 8.346770 0.355906 0.594368 0.321839
ENSG00000128908 OV Del 16.983256 0.359574 0.593811 0.616580