Ensembl ID ENSG00000127989 Gene ID 7978 Accession 21463
Gene Symbol MTERF1 Alias MTERF Full Name mitochondrial transcription termination factor 1
Position 7 : 91870929 - 91880702 Length 9774 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding. [provided by RefSeq, Jul 2008]

ENSG00000127989 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000127989 MTERF1 0.74 1.21e-11 BLCA
ENSG00000127989 MTERF1 0.96 1.14e-18 KICH
ENSG00000127989 MTERF1 1.28 1.63e-36 LUSC
ENSG00000127989 MTERF1 0.59 7.84e-14 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000127989 MTERF1 tumor 28931069
ENSG00000127989 MTERF1 tumor 31516563
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000127989 MTERF1 MESO 0.0086 low
ENSG00000127989 MTERF1 UCEC 0.015 high
ENSG00000127989 MTERF1 ACC 0.045 low
ENSG00000127989 MTERF1 LUSC 0.00021 low
ENSG00000127989 MTERF1 LUAD 0.024 low
ENSG00000127989 MTERF1 THYM 0.0088 low
ENSG00000127989 MTERF1 BRCA 0.0018 low
ENSG00000127989 MTERF1 COAD 0.018 high
ENSG00000127989 MTERF1 ESCA 0.046 high
ENSG00000127989 MTERF1 KIRC 0.004 low
ENSG00000127989 MTERF1 PRAD 0.041 low
ENSG00000127989 MTERF1 TGCT 0.042 low
ENSG00000127989 MTERF1 BLCA 0.004 low
ENSG00000127989 MTERF1 LAML 0.045 low
ENSG00000127989 MTERF1 SKCM 0.00072 low
ENSG00000127989 MTERF1 CESC 0.039 high
ENSG00000127989 MTERF1 LIHC 0.0012 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000127989 MTERF1 LUSC Amp 2.664256 0.253382 0.548909 0.528942
ENSG00000127989 MTERF1 PAAD Amp 1.403195 0.105568 0.447415 0.304348
ENSG00000127989 MTERF1 ESCA Amp 10.909210 0.697879 0.792004 0.619565
ENSG00000127989 MTERF1 HNSC Amp 6.747154 0.230966 0.626296 0.316092
ENSG00000127989 MTERF1 LIHC Amp 1.857709 0.142869 0.645003 0.332432
ENSG00000127989 MTERF1 TGCT Amp 1.190440 0.140338 0.532682 0.773333
ENSG00000127989 MTERF1 STAD Amp 19.031754 0.461042 0.750965 0.458050
ENSG00000127989 MTERF1 PRAD Amp 1.344913 0.055333 0.505939 0.215447