Ensembl ID ENSG00000126749 Gene ID 10436 Accession 16912
Gene Symbol EMG1 Alias C2F;NEP1;Grcc2f Full Name EMG1 N1-specific pseudouridine methyltransferase
Position 12 : 6970913 - 6979936 Length 9024 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary This gene encodes an essential, conserved eukaryotic protein that methylates pseudouridine in 18S rRNA. The related protein in yeast is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

ENSG00000126749 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000126749 EMG1 0.40 1.04e-11 BRCA
ENSG00000126749 EMG1 0.66 3.03e-14 COAD
ENSG00000126749 EMG1 0.80 2.09e-16 LUSC
ENSG00000126749 EMG1 0.68 5.51e-12 KIRP
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000126749 EMG1 ovarian cancer 24240090
ENSG00000126749 EMG1 colon cancer 29992185
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000126749 EMG1 MESO 0.028 high
ENSG00000126749 EMG1 SARC 0.023 high
ENSG00000126749 EMG1 UVM 0.00041 high
ENSG00000126749 EMG1 PAAD 0.043 low
ENSG00000126749 EMG1 UCEC 0.0045 low
ENSG00000126749 EMG1 LGG 0.013 low
ENSG00000126749 EMG1 LUSC 0.0083 low
ENSG00000126749 EMG1 READ 0.0031 high
ENSG00000126749 EMG1 KIRP 0.011 high
ENSG00000126749 EMG1 KICH 0.002 high
ENSG00000126749 EMG1 LUAD 0.015 high
ENSG00000126749 EMG1 PCPG 0.012 high
ENSG00000126749 EMG1 THYM 0.0021 low
ENSG00000126749 EMG1 BRCA 0.0077 low
ENSG00000126749 EMG1 ESCA 0.00089 high
ENSG00000126749 EMG1 OV 0.029 high
ENSG00000126749 EMG1 GBM 0.019 high
ENSG00000126749 EMG1 LIHC 0.00047 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000126749 EMG1 LUAD Del 2.107926 0.068400 0.345401 0.246124
ENSG00000126749 EMG1 LGG Amp 9.238738 0.143668 0.770779 0.130604
ENSG00000126749 EMG1 PAAD Del 1.094191 0.054133 0.396373 0.146739
ENSG00000126749 EMG1 STAD Del 0.894596 0.063584 0.403269 0.156463
ENSG00000126749 EMG1 OV Amp 1.520813 0.358565 0.903892 0.544041