Ensembl ID ENSG00000126432 Gene ID 25824 Accession 9355
Gene Symbol PRDX5 Alias PLP;ACR1;B166;PRXV;PMP20;PRDX6;prx-V;SBBI10;AOEB166;HEL-S-55 Full Name peroxiredoxin 5
Position 11 : 64318121 - 64321811 Length 3691 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene. [provided by RefSeq, Nov 2017]

ENSG00000126432 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000126432 PRDX5 1.09 1.18e-18 KICH
ENSG00000126432 PRDX5 -0.8 2.87e-11 STAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000126432 PRDX5 tumor 12960131
ENSG00000126432 PRDX5 malignant adrenocortical tumors 18324346
ENSG00000126432 PRDX5 tumors 20307276
ENSG00000126432 PRDX5 tumor 21641069
ENSG00000126432 PRDX5 tumors 22110952
ENSG00000126432 PRDX5 endometrial cancer 22783432
ENSG00000126432 PRDX5 breast tumor 24649208
ENSG00000126432 PRDX5 tumours 26722077
ENSG00000126432 PRDX5 AML 27621603
ENSG00000126432 PRDX5 cancer 28357082
ENSG00000126432 PRDX5 gastric cancer 28423550
ENSG00000126432 PRDX5 breast cancer 28878155
ENSG00000126432 PRDX5 endometrial cancer 29541251
ENSG00000126432 PRDX5 ovarian cancer 30104402
ENSG00000126432 PRDX5 lung cancer 30568461
ENSG00000126432 PRDX5 Colon Cancer 31262894
ENSG00000126432 PRDX5 Gastric Cancer 31280208
ENSG00000126432 PRDX5 Colon Cancer 31704839
ENSG00000126432 PRDX5 tumors 31899687
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000126432 PRDX5 MESO 0.00044 low
ENSG00000126432 PRDX5 UVM 0.0076 high
ENSG00000126432 PRDX5 PAAD 0.02 high
ENSG00000126432 PRDX5 LGG 0.00017 low
ENSG00000126432 PRDX5 LUSC 0.033 low
ENSG00000126432 PRDX5 HNSC 0.0063 high
ENSG00000126432 PRDX5 READ 0.027 high
ENSG00000126432 PRDX5 KIRP 0.0045 low
ENSG00000126432 PRDX5 PCPG 0.033 low
ENSG00000126432 PRDX5 UCS 0.014 low
ENSG00000126432 PRDX5 OV 0.00058 low
ENSG00000126432 PRDX5 SKCM 0.02 high
ENSG00000126432 PRDX5 LIHC 0.00068 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000126432 PRDX5 UCS Amp 0.751957 0.502256 0.818521 0.303571
ENSG00000126432 PRDX5 HNSC Amp 4.014626 0.186705 0.448798 0.264368
ENSG00000126432 PRDX5 BRCA Del 3.577834 0.084908 0.441998 0.226852