Ensembl ID
ENSG00000125835
Gene ID
6628
Accession
11153
Gene Symbol
SNRPB
Alias
COD;CCMS;SNRPB1;SmB/B';Sm-B/B';snRNP-B;SmB/SmB'
Full Name
small nuclear ribonucleoprotein polypeptides B and B1
Position
20 : 2461634 - 2470853
Length
9220 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs snRNA RBP type
Canonical_RBPs
Summary
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008]
ENSG00000125835 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000125835
SNRPB
0.63
2.33e-14
KIRC
ENSG00000125835
SNRPB
0.69
5.91e-12
HNSC
ENSG00000125835
SNRPB
1.09
9.91e-13
BLCA
ENSG00000125835
SNRPB
1.26
8.73e-74
BRCA
ENSG00000125835
SNRPB
1.11
7.27e-19
COAD
ENSG00000125835
SNRPB
1.00
7.08e-18
KICH
ENSG00000125835
SNRPB
1.38
5.26e-54
LUSC
ENSG00000125835
SNRPB
0.98
2.56e-23
KIRP
ENSG00000125835
SNRPB
1.14
8.47e-27
LIHC
ENSG00000125835
SNRPB
1.08
5.79e-20
UCEC
ENSG00000125835
SNRPB
1.21
9.52e-11
ESCA
ENSG00000125835
SNRPB
0.77
1.78e-12
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000125835
SNRPB
cancer
24726865
ENSG00000125835
SNRPB
cancer
27287018
ENSG00000125835
SNRPB
AML
31448224
ENSG00000125835
SNRPB
tumor
31511502
ENSG00000125835
SNRPB
tumor
31930637
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000125835
SNRPB
MESO
0.00037
high
show
ENSG00000125835
SNRPB
SARC
0.0074
high
show
ENSG00000125835
SNRPB
CHOL
0.033
high
show
ENSG00000125835
SNRPB
UVM
0.00012
high
show
ENSG00000125835
SNRPB
UCEC
0.038
high
show
ENSG00000125835
SNRPB
ACC
0.01
high
show
ENSG00000125835
SNRPB
LGG
0.00026
high
show
ENSG00000125835
SNRPB
LUSC
0.015
high
show
ENSG00000125835
SNRPB
HNSC
0.021
high
show
ENSG00000125835
SNRPB
READ
0.023
low
show
ENSG00000125835
SNRPB
KICH
0.011
high
show
ENSG00000125835
SNRPB
LUAD
0.012
high
show
ENSG00000125835
SNRPB
PCPG
0.027
high
show
ENSG00000125835
SNRPB
THYM
0.01
low
show
ENSG00000125835
SNRPB
COAD
0.018
high
show
ENSG00000125835
SNRPB
ESCA
0.0033
high
show
ENSG00000125835
SNRPB
OV
0.033
low
show
ENSG00000125835
SNRPB
DLBC
0.019
low
show
ENSG00000125835
SNRPB
KIRC
2e-04
high
show
ENSG00000125835
SNRPB
LAML
0.0036
high
show
ENSG00000125835
SNRPB
GBM
0.046
low
show
ENSG00000125835
SNRPB
CESC
0.0025
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000125835
SNRPB
READ
Del
1.114082
0.083987
0.552186
0.296970
ENSG00000125835
SNRPB
COAD
Del
1.722271
0.053532
0.553067
0.188470
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