Ensembl ID ENSG00000125630 Gene ID 84172 Accession 20454
Gene Symbol POLR1B Alias A135;RPA2;TCS4;RPA135;Rpo1-2 Full Name RNA polymerase I subunit B
Position 2 : 112541915 - 112579818 Length 37904 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM, Mar 2008]

ENSG00000125630 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000125630 POLR1B 1.19 2.95e-73 COAD
ENSG00000125630 POLR1B 1.19 1.10e-20 READ
ENSG00000125630 POLR1B 0.85 1.35e-27 LUSC
ENSG00000125630 POLR1B 0.95 1.67e-22 STAD
ENSG00000125630 POLR1B 0.66 1.28e-22 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000125630 POLR1B non-small cell lung cancer 31897183
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000125630 POLR1B PAAD 0.00046 high
ENSG00000125630 POLR1B ACC 0.0028 high
ENSG00000125630 POLR1B LGG 0.027 high
ENSG00000125630 POLR1B LUSC 0.015 low
ENSG00000125630 POLR1B HNSC 0.0053 high
ENSG00000125630 POLR1B READ 0.043 low
ENSG00000125630 POLR1B PRAD 0.016 high
ENSG00000125630 POLR1B SKCM 0.022 low
ENSG00000125630 POLR1B CESC 0.022 low
ENSG00000125630 POLR1B LIHC 0.0027 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency