Ensembl ID ENSG00000125166 Gene ID 2806 Accession 4433
Gene Symbol GOT2 Alias KAT4;DEE82;KATIV;KYAT4;mitAAT Full Name glutamic-oxaloacetic transaminase 2
Position 16 : 58707131 - 58734326 Length 27196 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

ENSG00000125166 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000125166 -1.0 6.72e-42 KIRC
ENSG00000125166 -0.5 2.04e-11 HNSC
ENSG00000125166 0.80 2.98e-33 BRCA
ENSG00000125166 0.93 9.60e-17 KICH
ENSG00000125166 1.11 4.59e-36 LUSC
ENSG00000125166 -1.2 1.49e-13 GBM
ENSG00000125166 -1.0 3.02e-14 LIHC
ENSG00000125166 -2.8 5.70e-29 CHOL
ENSG00000125166 0.54 4.69e-13 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000125166 colorectal cancer 10518104
ENSG00000125166 tumour 10849370
ENSG00000125166 tumor 11103817
ENSG00000125166 cancer 11410510
ENSG00000125166 tumor 11752453
ENSG00000125166 tumour 12922171
ENSG00000125166 tumor 1376954
ENSG00000125166 colorectal cancer 15138477
ENSG00000125166 prostate cancer 15500004
ENSG00000125166 prostate cancer 15724839
ENSG00000125166 pancreatic cancer 15753353
ENSG00000125166 tumour 15922867
ENSG00000125166 cancer 15958538
ENSG00000125166 cancers 16374067
ENSG00000125166 bladder cancer 16400682
ENSG00000125166 breast cancer 16471039
ENSG00000125166 colorectal cancers 16489072
ENSG00000125166 tumours 16508338
ENSG00000125166 tumour 16759896
ENSG00000125166 breast cancer 17428383
ENSG00000125166 Cancer 17485234
ENSG00000125166 tumor 17639056
ENSG00000125166 laryngeal cancer 18335753
ENSG00000125166 breast cancer 18359695
ENSG00000125166 prostate cancer 18360704
ENSG00000125166 tumours 18544163
ENSG00000125166 endometrial cancer 18729184
ENSG00000125166 bladder cancer 19115207
ENSG00000125166 tumor 19337991
ENSG00000125166 tumors 19540848
ENSG00000125166 breast cancer 19842034
ENSG00000125166 prostate cancer 19956834
ENSG00000125166 tumour 20122155
ENSG00000125166 tumor 20834042
ENSG00000125166 tumor 20975997
ENSG00000125166 Cancer 21203453
ENSG00000125166 pancreatic cancer 21251264
ENSG00000125166 tumors 21399875
ENSG00000125166 tumor 21566527
ENSG00000125166 kidney cancer 21767383
ENSG00000125166 tumor 21993546
ENSG00000125166 gastric cancer 22172348
ENSG00000125166 cancer, kidney 22234525
ENSG00000125166 metastatic prostate cancer 23171028
ENSG00000125166 tumour 23242471
ENSG00000125166 tumor 24051694
ENSG00000125166 prostate cancer 24167657
ENSG00000125166 prostate cancer 24189640
ENSG00000125166 breast cancer 24304688
ENSG00000125166 cancer 24500438
ENSG00000125166 tumor 24520215
ENSG00000125166 tumor 24713431
ENSG00000125166 tumor 24719358
ENSG00000125166 tumour 24731659
ENSG00000125166 tumor 24779988
ENSG00000125166 DLBCL 25114248
ENSG00000125166 pancreatic tumor 25755250
ENSG00000125166 tumor 25796556
ENSG00000125166 breast cancer 25924435
ENSG00000125166 tumour 26239462
ENSG00000125166 tumor 26513060
ENSG00000125166 cancer 26682255
ENSG00000125166 tumor 26685086
ENSG00000125166 malignant brain tumors 26957635
ENSG00000125166 cancer 27121919
ENSG00000125166 tumour 27187749
ENSG00000125166 tumors 27446562
ENSG00000125166 prostate cancer 27471561
ENSG00000125166 tumors 27687006
ENSG00000125166 tumour 27816807
ENSG00000125166 gastric cancer 27884752
ENSG00000125166 tumor 27993630
ENSG00000125166 colon cancer 28007957
ENSG00000125166 breast cancers 28124996
ENSG00000125166 tumour 28155592
ENSG00000125166 gastric cancer 28180141
ENSG00000125166 GBM 28491867
ENSG00000125166 cancer 28545132
ENSG00000125166 prostate cancer 28597850
ENSG00000125166 Breast Cancer 28701570
ENSG00000125166 tumors 28720665
ENSG00000125166 cancer 28811348
ENSG00000125166 pancreatic cancer 29352139
ENSG00000125166 Breast Cancer 29437708
ENSG00000125166 tumor 29453741
ENSG00000125166 AMLs 29512829
ENSG00000125166 liver cancer 29880886
ENSG00000125166 cancer 29911740
ENSG00000125166 cancers 30021130
ENSG00000125166 cancer 30050129
ENSG00000125166 Tumor 30100196
ENSG00000125166 cancer 30167092
ENSG00000125166 cancer 30242145
ENSG00000125166 prostate cancer 30255424
ENSG00000125166 tumor 30302195
ENSG00000125166 bladder cancer 30526555
ENSG00000125166 breast cancer 30714292
ENSG00000125166 tumor 30755372
ENSG00000125166 tumour 30847246
ENSG00000125166 tumor 30858360
ENSG00000125166 tumors 30926650
ENSG00000125166 tumour 31082572
ENSG00000125166 breast cancer 31105883
ENSG00000125166 cancer 31143113
ENSG00000125166 cancer 31170472
ENSG00000125166 tumour 31334678
ENSG00000125166 tumor 31410698
ENSG00000125166 tumour 31565753
ENSG00000125166 tumor 31576171
ENSG00000125166 tumor 31602654
ENSG00000125166 tumours 31725814
ENSG00000125166 tumour 31738794
ENSG00000125166 breast cancer 31755351
ENSG00000125166 AML 31935373
ENSG00000125166 tumor 6935474
ENSG00000125166 tumor 8415623
ENSG00000125166 colon cancers 8515653
ENSG00000125166 tumor 8895735
ENSG00000125166 tumors 9307301
ENSG00000125166 tumors 9664136
ENSG00000125166 tumor 9919620
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000125166 MESO 0.00017 high
ENSG00000125166 SARC 0.0046 high
ENSG00000125166 CHOL 0.016 high
ENSG00000125166 PAAD 0.022 low
ENSG00000125166 UCEC 0.0032 low
ENSG00000125166 ACC 0.0025 low
ENSG00000125166 HNSC 0.00017 high
ENSG00000125166 KIRP 3e-04 low
ENSG00000125166 KICH 0.00075 low
ENSG00000125166 LUAD 0.0055 high
ENSG00000125166 PCPG 0.012 high
ENSG00000125166 THYM 0.034 high
ENSG00000125166 BRCA 0.00088 high
ENSG00000125166 COAD 0.035 low
ENSG00000125166 ESCA 0.006 high
ENSG00000125166 OV 0.028 low
ENSG00000125166 LAML 0.00022 high
ENSG00000125166 GBM 0.0025 low
ENSG00000125166 SKCM 0.00022 high
ENSG00000125166 CESC 0.032 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000125166 TGCT Amp 0.676527 0.115005 0.628345 0.126667
ENSG00000125166 UCEC Del 3.231022 0.074520 0.629540 0.282004