Ensembl ID ENSG00000125107 Gene ID 23019 Accession 7877
Gene Symbol CNOT1 Alias NOT1;CDC39;HPE12;NOT1H;VIBOS;AD-005 Full Name CCR4-NOT transcription complex subunit 1
Position 16 : 58519951 - 58629885 Length 109935 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Enables armadillo repeat domain binding activity; molecular adaptor activity; and nuclear receptor binding activity. Contributes to poly(A)-specific ribonuclease activity. Involved in several processes, including negative regulation of signal transduction; positive regulation of cytoplasmic mRNA processing body assembly; and regulation of gene expression. Located in P-body and cytosol. Part of CCR4-NOT complex. Implicated in holoprosencephaly. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000125107 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000125107 CNOT1 breast cancer 16778766
ENSG00000125107 CNOT1 tumors 25980492
ENSG00000125107 CNOT1 tumor 26807845
ENSG00000125107 CNOT1 tumors 27626165
ENSG00000125107 CNOT1 tumors 28188704
ENSG00000125107 CNOT1 breast cancer 29669595
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000125107 CNOT1 MESO 0.027 high
ENSG00000125107 CNOT1 UVM 0.025 high
ENSG00000125107 CNOT1 PAAD 0.02 high
ENSG00000125107 CNOT1 READ 0.029 low
ENSG00000125107 CNOT1 KIRP 0.039 high
ENSG00000125107 CNOT1 BRCA 0.015 high
ENSG00000125107 CNOT1 COAD 0.032 high
ENSG00000125107 CNOT1 OV 0.036 high
ENSG00000125107 CNOT1 PRAD 0.026 high
ENSG00000125107 CNOT1 GBM 0.013 low
ENSG00000125107 CNOT1 CESC 0.047 high
ENSG00000125107 CNOT1 LIHC 0.035 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000125107 CNOT1 TGCT Amp 0.676527 0.115005 0.628345 0.126667
ENSG00000125107 CNOT1 UCEC Del 3.321336 0.075324 0.629540 0.282004